INVITRO COMPARISON OF THE CYTOTOXICITY OF 12 ENDODONTIC MATERIALS USING A NEW TECHNIQUE

被引：25

作者：

MERYON, SD

BROOK, AM

机构：

[1] Department of Oral Pathology, Dental School, University of Birmingham, Birmingham

来源：

INTERNATIONAL ENDODONTIC JOURNAL | 1990年 / 23卷 / 04期

关键词：

D O I：

10.1111/j.1365-2591.1990.tb00101.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Summary. An in vitro method for the cytotoxicity testing of endodontic materials is described which aims to simulate the clinical situation. Materials can be tested in the presence or absence of a compacted layer of dentine chips mimicking the periapical dentine plug. A total of twelve materials were tested. In the absence of dentine, Kloroperka, Biocalex, Diaket and Endomethasone were slightly cytotoxic; AH26 with and without silver, Sealapex, Tubliseal and Kerr's pulp canal sealer were moderately cytotoxic, while Forfenan, Spad and Kri paste were strongly cytotoxic. In the presence of dentine the cytotoxicity of these materials was considerably reduced, with the exception of Endomethasone, Forfenan, Spad and Kri paste. The method provides a satisfactory alternative to implantation testing and is an inexpensive and reproducible test system in which dentine can be incorporated. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：203 / 210

页数：8

共 27 条

[1]

Abbott P.V., Heithersay G.S., Hume W.R., Release and diffusion through human tooth roots in vitro of corticosteroid and tetracycline trace molecules from Ledermix paste, Endodontics and Dental Traumatology, 4, pp. 55-62, (1988)

[2]

Browne R.M., Friend L.A., An investigation into the irritant properties of some root filling materials, Archives of Oral Biology, 13, pp. 1355-1369, (1968)

[3]

Eriksen H.M., ORstavol D, Kerekes K., Healing of a pical periodontitis after endodontic treatment using three different root canal seakers, Endodontics and Dental Traumatology, 4, pp. 114-117, (1988)

[4]

Kettering J.D., Torabinejad M., Cytotoxicity of root canal sealers: a study using HeLa cells and fibroblasts, International Endodontic Journal, 17, pp. 60-66, (1984)

[5]

Lambjerg-Hansen H., Vital pulpectomy and root filling with N2 of Endomethasone, International Endodontic Journal, 20, pp. 194-204, (1987)

[6]

Meryon S.D., The influence of dentine on the in vitro cytotoxicity testing of dental restorative materials, Journal of Biomedical Materials Research, 18, pp. 771-779, (1984)

[7]

Meryon S.D., Jakeman K.J., An in vitro study of the role of dentine in moderating the cytotoxicity of zinc oxide eugenol cement, Biomaterials, 7, pp. 459-462, (1986)

[8]

Mjor I.A., Endodontic materials: reactor response, Advances in Dental Research, 2, pp. 25-28, (1988)

[9]

ORstavik D., Endodontic material, Advances in Dental Research, 2, pp. 12-24, (1988)

[10]

ORstavik D., Mjo I.A., Endodontics, Dental Materials: Biological Properties and Clinical Evaluations, pp. 125-135, (1985)

← 1 2 3 →