ADIPOKINETIC HORMONE CONTROLS LIPID-METABOLISM IN ADULTS AND CARBOHYDRATE-METABOLISM IN LARVAE OF MANDUCA-SEXTA

被引：57

作者：

ZIEGLER, R

ECKART, K

LAW, JH

机构：

[1] UNIV ARIZONA,CTR INSECT SCI,TUCSON,AZ 85721

[2] MAX PLANCK INST EXPTL MED,W-3400 GOTTINGEN,GERMANY

来源：

PEPTIDES | 1990年 / 11卷 / 05期

关键词：

Adipokinetic hormone; FAB tandem mass spectrometry; Glycogen phosphorylase activating hormone; Glycogen phosphorylase activation; Lipid mobilization;

D O I：

10.1016/0196-9781(90)90030-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The peptide hormone which controls activation of fat body glycogen phosphorylase in starving larvae of Manduca sexta was isolated from larval corpora cardiaca and sequenced by FAB tandem mass spectrometry. It was found to be identical with Manduca AKH. This, together with earlier observations, demonstrates that in M. sexta AKH controls glycogen phosphorylase activation in starving larvae while in adults it controls lipid mobilization during flight. Larval corpora cardiaca contain about 10 times less AKH than the corpoca cardiaca of adults. The corpora cardiaca of M. sexta appear to contain only one AKH. © 1990.

引用

页码：1037 / 1040

页数：4

共 21 条

[1] SEQUENCE DETERMINATION OF N-TERMINAL AND C-TERMINAL BLOCKED PEPTIDES CONTAINING N-ALKYLATED AMINO-ACIDS AND STRUCTURE DETERMINATION OF THESE AMINO-ACID CONSTITUENTS BY USING FAST-ATOM-BOMBARDMENT TANDEM MASS-SPECTROMETRY [J].