ENZYMATIC GLYCOSYLATION OF O-GLYCOPEPTIDES

被引：29

作者：

SCHULTZ, M ^{[1
]}

KUNZ, H ^{[1
]}

机构：

[1] UNIV MAINZ,INST ORGAN CHEM,BECHERWEG 18-20,W-6500 MAINZ,GERMANY

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(00)79082-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

O-Glycosylation of serine derivatives carried out with N-urethane protected glucosamine yields O-glycopeptides which are regio-and stereoselectively galactosylated with the aid of beta-1,4-galactosyltransferase (EC2.4.1.22).

引用

页码：5319 / 5322

页数：4

共 17 条

[1] THE USE OF AN IMMOBILIZED CYCLIC MULTIENZYME SYSTEM TO SYNTHESIZE BRANCHED PENTA-SACCHARIDES AND HEXA-SACCHARIDES ASSOCIATED WITH BLOOD-GROUP I EPITOPES [J].

AUGE, C ;

MATHIEU, C ;

MERIENNE, C .

CARBOHYDRATE RESEARCH, 1986, 151 :147-156

[2] ENZYMIC-SYNTHESIS OF THE SIALYLGLYCOPEPTIDE, ALPHA-D-NEUPAC-(2-]6)-BETA-D-GALP-(1-]4)-BETA-D-GLCPNAC-(1-]4N)-L-ASN [J].

AUGE, C ;

GAUTHERON, C ;

PORA, H .

CARBOHYDRATE RESEARCH, 1989, 193 :288-293

[3] THE USE OF N-ALKOXYCARBONYL DERIVATIVES OF 2-AMINO-2-DEOXY-D-GLUCOSE AS DONORS IN GLYCOSYLATION REACTIONS [J].

BOULLANGER, P ;

JOUINEAU, M ;

BOUAMMALI, B ;

LAFONT, D ;

DESCOTES, G .

CARBOHYDRATE RESEARCH, 1990, 202 :151-164

[4] A NOVEL PROMOTER FOR THE EFFICIENT CONSTRUCTION OF 1,2-TRANS LINKAGES IN GLYCOSIDE SYNTHESIS, USING THIOGLYCOSIDES AS GLYCOSYL DONORS [J].

FUGEDI, P ;

GAREGG, PJ .

CARBOHYDRATE RESEARCH, 1986, 149 (01) :C9-C12

[5] AMINO-SUGARS .50. SYNTHESIS OF DERIVATIVES OF O-(2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYL)-L-SERINE [J].

GARG, HG ;

JEANLOZ, RW .

CARBOHYDRATE RESEARCH, 1976, 49 (JUL) :482-488

[6]

HOLT GD, 1986, J BIOL CHEM, V261, P8049

[7]

KAUTH H, 1983, LIEBIGS ANN CHEM, P360

[8]

KUNZ H, 1990, SYNLETT, P631

[9] THE ALLYLOXYCARBONYL (ALOC) MOIETY - CONVERSION OF AN UNSUITABLE INTO A VALUABLE AMINO PROTECTING GROUP FOR PEPTIDE-SYNTHESIS [J].

KUNZ, H ;

UNVERZAGT, C .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1984, 23 (06) :436-437

[10]

Kunz H., 1984, ANGEW CHEM, V96, P426

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