INFLUENCE OF CALCITONIN TREATMENT ON THE OSTEOCALCIN CONCENTRATION IN THE ALGODYSTROPHY OF BONE

被引：12

作者：

SAWICKI, A

SZULC, P

SOBCZYK, T

GOLISZEWSKI, J

GARNIER, P

LABUSZEWSKI, R

机构：

[1] Mineral Metabolism and Bone Pathology Unit, Dept. Neuroendocrinology, Medical Center for Postgraduate Education, Orthopaedic Hosptial, Warsaw, 02315

[2] Dept. Endocrinology, Medical Center for Postgraduate Education, Warsaw

[3] Orthopaedic Hospital, Warsaw

[4] Fondation Recherche en Hormonologie, Paris-Fresnes

来源：

CLINICAL RHEUMATOLOGY | 1992年 / 11卷 / 03期

关键词：

ALGODYSTROPHY; OSTEOCALCIN; ALKALINE PHOSPHATASE; CALCITONIN TREATMENT;

D O I：

10.1007/BF02207191

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Algodystrophy (AD) attacks all tissues in the affected region and results in the rapid demineralization of bones. Osteocalcin (OC) and alkaline phosphatase (AP) are markers of bone turnover. Calcitonin is the treatment of choice of AD. Two groups of patients were studied : Group I (n = 8) - acute stage of AD (before and during the calcitonin treatment), Group II (n = 5) - late chronic stage of AD. In the acute stage of AD both OC level and AP activity were increased. They were normal in the chronic stage of AD. During the calcitonin treatment OC level normalized after 14 days and then increased again. During the treatment, AP activity temporarily increased and then returned to the initial level. We confirm that an increased bone turnover is observed in the acute stage of AD. Discrepancy between OC level and AP activity reflects the local metabolic disturbances. Salmon calcitonin inhibits the algodystrophic process and probably contributes to the activation of the skeletal restoration.

引用

页码：346 / 350

页数：5

共 38 条

[1]

Doury P., Algodystrophy. Reflex sympathetic dystrophy syndrome, Clin Rheumatol, 7, pp. 173-80, (1987)

[2]

Carlson T., Jacobs A.M., Reflex sympathetic dystrophy syndrome, J Foot Surg, 25, pp. 149-153, (1986)

[3]

Doury P., Pattin S., Eulry F., Faquert P., Granier R., Graillard J.F., L'algodystropiie du genou. A propos d'une série de 125 observations, Rev Rhum Mal Osteoartic, 54, pp. 655-659, (1987)

[4]

Reginster J.Y., Gritten C., Franchimont P., L'olgodystrophie, Rev Méd Liège, 41, pp. 996-1003, (1986)

[5]

Renier J.C., Basle M., Arlet J., Seret P., L'os et le métabolisme phosphocalcique dans l'algodystrophie, Rev Rhum Mal Osteoartic, 50, pp. 23-31, (1983)

[6]

DeGuembecker W., DeGuembecker C., Duriez R., Duriez J., Apport de l'absorption photonique dans le diagnostic des algodystrophis décalcifiantes des pieds, Rev Rhum Mal Osteoartic, 49, pp. 887-890, (1982)

[7]

Krawzak H.W., Lindecken K.D., Beyer H.K., Mayer M., Quantifizierung von Mineralisationsprozessen bei posttraumatischer Algodystrophie mittels computerotomographischer Densitometrie, Z Orthop, 127, pp. 202-206, (1989)

[8]

Sarrat P., Acquaviva P.C., Laforgue P., Zakarian H., Lopez M., Bouscarle B., L'algodystrophie de la tête fémorale. Apport des nouvelles méthodes d'imagerie, J Radiol, 69, pp. 495-500, (1988)

[9]

Constantinesco A., Brunot B., Demangeat J.L., Foucher G., Farcot J.M., Apport de la scintigraphie osseuse en trois phases au diagnostic précoce de l'algodystrophie, Ann Chir Main, 5, pp. 93-104, (1986)

[10]

Rutishauser E., Vernet A., Marabraud A., L'ostéoporose posttraumatique. Etude histopathologique, Acta Chir Belg, pp. 123-148, (1956)

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