POST-MORTEM KINETICS OF SECOBARBITAL

被引：7

作者：

QUATREHOMME, G ^{[1
]}

BOURRET, F ^{[1
]}

ZHIOUA, M ^{[1
]}

LAPALUS, P ^{[1
]}

OLLIER, A ^{[1
]}

机构：

[1] FAC MED NICE,PHARMACOL EXPTL & CLIN LAB,F-06034 NICE,FRANCE

来源：

FORENSIC SCIENCE INTERNATIONAL | 1990年 / 44卷 / 2-3期

关键词：

Barbiturates; Post-mortem kinetics;

D O I：

10.1016/0379-0738(90)90241-P

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Post-mortem changes in barbiturate concentrations were evidenced using a rat-secobarbital model. The method used for the extraction and HPLC assay of barbiturates is suitable for all biologic fluids and post-mortem tissues. Kinetic data obtained is of excellent quality. Various modelization constants wer defined. This experimental work emphasizes the difficulty of post-mortem toxicology, as concentrations found at the time autopsy may be different from concentrations at the time of death, in blood as well as in tissues. © 1990.

引用

页码：117 / 123

页数：7

共 10 条

[1]

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[2]

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[3]

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[4]

MANGIN P, 1985, THESIS STRASBOURG

[5]

ORZELEK RM, 1979, J FORENSIC SCI, V24, P554

[6] POST-MORTEM CHANGES IN TISSUE LEVELS OF SODIUM SECOBARBITAL [J].

PARKER, JM ;

WINEK, CL ;

SHANOR, SP .

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[7]

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[8]

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[9]

VIALA A, 1986, J MED LEG DROIT MED, V29, P133

[10]

VORPAHL TE, 1978, J FORENSIC SCI, V23, P329

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