EXPRESSION OF THE PS2 GENE IN BREAST TISSUES ASSESSED BY PS2-MESSENGER RNA ANALYSIS AND PS2-PROTEIN RADIOIMMUNOASSAY

被引：6

作者：

HAHNEL, E

ROBBINS, P

HARVEY, J

STERRETT, G

HAHNEL, R

机构：

[1] The Queen Elizabeth II Medical Centre, University Department of Pathology, Nedlands, 6009, Western Australia

来源：

BREAST CANCER RESEARCH AND TREATMENT | 1992年 / 24卷 / 01期

关键词：

BREAST TISSUE; PS2-MESSENGER RNA; PS2; PROTEIN; RADIOIMMUNOASSAY;

D O I：

10.1007/BF01832360

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The expression of the pS2 gene in breast tissues was assessed by measuring pS2-protein using a radioimmunoassay, and by determining pS2-mRNA using Northern blotting. There was a good correlation between the two measurements, indicating that expression of the pS2 gene in breast tissues may be assessed by either method. Since radioimmunoassay is technically easier and more efficient than Northern blotting, radioimmunoassay will be the method of choice in routine applications.

引用

页码：71 / 74

页数：4

共 9 条

[1]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[2]

FOEKENS JA, 1990, CANCER RES, V50, P3832

[3] PROGNOSTIC VALUE OF PS2 PROTEIN AND RECEPTORS FOR EPIDERMAL GROWTH-FACTOR (EGF-R), INSULIN-LIKE GROWTH FACTOR-I (IGF-1-R) AND SOMATOSTATIN (SS-R) IN PATIENTS WITH BREAST AND OVARIAN-CANCER [J].