LOCALIZED PROTON MR SPECTROSCOPY OF CITRATE INVITRO AND OF THE HUMAN PROSTATE INVIVO AT 1.5-T

被引:72
作者
SCHICK, F
BONGERS, H
KURZ, S
JUNG, WI
PFEFFER, M
LUTZ, O
机构
[1] UNIV TUBINGEN, INST PHYS, MORGENSTELLE, W-7400 TUBINGEN 1, GERMANY
[2] UNIV TUBINGEN, DEPT DIAGNOST RADIOL, W-7400 TUBINGEN 1, GERMANY
关键词
PROTON MR SPECTROSCOPY; PROSTATE TUMOR; CITRATE; LOCALIZED MR SPECTROSCOPY;
D O I
10.1002/mrm.1910290109
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Citrate is a secretory product of the normal prostate, a lack of citrate in prostate tissue is expected to be pathognomonic for adenocarcinoma. In the present study proton AB-signal characteristics of citrate at low field strength of 1.5 T were investigated by volume selective spectroscopic and theoretical methods. The nonappearance of fast phase modulation of the J-coupled system at low field strength in vivo is verified by measurements of sodium citrate solution. In vivo localized spectroscopy of small volume elements of (2 cm)3 with the double spin-echo method within the prostatic gland provides citrate signal reception even using a Helmholtz coil with 170-mm diameter. Volume selective proton spectra with different echo times are presented which are comparable to spectra acquired by former authors with endorectal coils.
引用
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页码:38 / 43
页数:6
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