GENETIC ALTERATIONS IN NONMELANOMA SKIN-CANCER

被引：49

作者：

REES, J

机构：

[1] University Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1994年 / 103卷 / 06期

关键词：

TUMOR SUPPRESSOR; ONCOGENE; P53; LOSS OF HETEROZYGOSITY;

D O I：

10.1111/1523-1747.ep12412256

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Non-melanoma skin cancer is common and offers unrivaled opportunities to relate genetic changes to clinical and biologic behavior. Recent technical advances in molecular biology render genetic analysis of even the smallest skin cancers possible. In this review I will discuss the role of p53 gene in skin carcinogenesis, putative tumor suppressor genes both on chromosome 9 and other chromosomes in non-melanolma skin cancer.

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收藏

页码：747 / 750

页数：4

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