DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .2. DISPOSITION AND PHARMACOKINETICS FOLLOWING INTRAVENOUS AND INTRAMUSCULAR ADMINISTRATION

被引：66

作者：

TAKAKURA, Y ^{[1
]}

ATSUMI, R ^{[1
]}

HASHIDA, M ^{[1
]}

SEZAKI, H ^{[1
]}

机构：

[1] KYOTO UNIV,FAC PHARMACEUT SCI,DEPT BASIC PHARMACEUT,SAKYO KU,KYOTO 606,JAPAN

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1987年 / 37卷 / 1-2期

关键词：

D O I：

10.1016/0378-5173(87)90019-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：145 / 154

页数：10

共 18 条

[1]

BARLOGIE B, 1980, CANCER RES, V40, P1973

[2]

BOLLMAN JL, 1948, J LAB CLIN MED, V33, P1349

[3]

HASHIDA M, 1984, DRUG METAB DISPOS, V12, P492

[4]

HASHIDA M, 1981, GANN, V72, P226

[5]

HASHIDA M, 1983, CHEM PHARM BULL, V31, P2055

[6]

HONDA K, 1985, JPN J CANC CHEMOTHER, V12, P530

[7] MITOMYCIN-C-DEXTRAN CONJUGATE - NOVEL HIGH MOLECULAR-WEIGHT PRO-DRUG OF MITOMYCIN-C [J].

KOJIMA, T ;

HASHIDA, M ;

MURANISHI, S ;

SEZAKI, H .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1980, 32 (01) :30-34

[8] A SIMPLIFIED METHOD OF SAMPLE PREPARATION FOR DETERMINATION OF TRITIUM CARBON-14 OR SULFUR-35 IN BLOOD OF TISSUE BY LIQUID SCINTILLATION COUNTING [J].

MAHIN, DT ;

LOFBERG, RT .

ANALYTICAL BIOCHEMISTRY, 1966, 16 (03) :500-&

[9]

MATSUMOTO S, 1985, CHEM PHARM BULL, V33, P2941

[10]

Poznansky M. J., 1980, DRUG DELIVERY SYSTEM, P253

← 1 2 →