THE LEAKS AND SLIPS OF BIOENERGETIC MEMBRANES

被引：47

作者：

BROWN, GC

机构：

[1] Biochemistry/Molecular Biology Dept., University College London, London WC1E 6BT, Gower Street

来源：

FASEB JOURNAL | 1992年 / 6卷 / 11期

关键词：

PROTON PERMEABILITY; PROTON STOICHIOMETRY; MEMBRANE PERMEABILITY; BIOENERGETICS; MITOCHONDRIA;

D O I：

10.1096/fasebj.6.11.1644259

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bioenergetic membranes use proton gradients to transduce energy. However, when the proton gradient is large 1) there is a passive leak of protons (and other ions) across these membranes, and 2) some proton pumps may fail to pump protons (a phenomenon known as slip). Leaks and slips may be an unavoidable consequence of membrane structure and cause significant wastage of free energy, but they may also have functional roles beneficial to the organism.

引用

页码：2961 / 2965

页数：5

共 51 条

[1] ENERGETICS OF EHRLICH ASCITES MITOCHONDRIA - MEMBRANE-POTENTIAL OF ISOLATED-MITOCHONDRIA AND MITOCHONDRIA WITHIN DIGITONIN-PERMEABILIZED CELLS
BOGUCKA, K
WRONISZEWSKA, A
BEDNAREK, M
DUSZYNSKI, J
WOJTCZAK, L
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1015 (03) : 503 - 509
[2] FACTORS REGULATING THE SLOW ELECTROGENIC PHASE IN GREEN-ALGAE AND HIGHER-PLANTS
BOUGESBOCQUET, B
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1981, 635 (02) : 327 - 340
[3] EVOLUTION OF ENERGY-METABOLISM - PROTON PERMEABILITY OF THE INNER MEMBRANE OF LIVER-MITOCHONDRIA IS GREATER IN A MAMMAL THAN IN A REPTILE
BRAND, MD
COUTURE, P
ELSE, PL
WITHERS, KW
HULBERT, AJ
[J]. BIOCHEMICAL JOURNAL, 1991, 275 : 81 - 86
[4] THE CONTRIBUTION OF THE LEAK OF PROTONS ACROSS THE MITOCHONDRIAL INNER MEMBRANE TO STANDARD METABOLIC-RATE
BRAND, MD
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1990, 145 (02) : 267 - 286
[5] THE PROTON LEAK ACROSS THE MITOCHONDRIAL INNER MEMBRANE
BRAND, MD
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1018 (2-3) : 128 - 133
[6] BROWN GC, 1989, J BIOL CHEM, V264, P14704
[7] ON THE NATURE OF THE MITOCHONDRIAL PROTON LEAK
BROWN, GC
BRAND, MD
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1059 (01) : 55 - 62
[8] CHANGES IN PERMEABILITY TO PROTONS AND OTHER CATIONS AT HIGH PROTON MOTIVE FORCE IN RAT-LIVER MITOCHONDRIA
BROWN, GC
BRAND, MD
[J]. BIOCHEMICAL JOURNAL, 1986, 234 (01) : 75 - 81
[9] CONTROL OF RESPIRATION AND OXIDATIVE-PHOSPHORYLATION IN ISOLATED RAT-LIVER CELLS
BROWN, GC
LAKINTHOMAS, PL
BRAND, MD
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 192 (02): : 355 - 362
[10] THE RELATION BETWEEN MEMBRANE IONIC CURRENT AND ATP SYNTHESIS IN CHROMATOPHORES FROM RHODOPSEUDOMONAS-CAPSULATA
CLARK, AJ
COTTON, NPJ
JACKSON, JB
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 723 (03) : 440 - 453

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