CAN PHAGE DEFENSE MAINTAIN COLICIN PLASMIDS IN ESCHERICHIA-COLI

被引：20

作者：

FELDGARDEN, M ^{[1
]}

GOLDEN, S ^{[1
]}

WILSON, H ^{[1
]}

RILEY, MA ^{[1
]}

机构：

[1] YALE UNIV,DEPT BIOL,NEW HAVEN,CT 06520

来源：

MICROBIOLOGY-UK | 1995年 / 141卷

关键词：

COLICIN PLASMID; CRYPTIC PLASMID; PHAGE RESISTANCE DEFENSE; ESCHERICHIA COLI;

D O I：

10.1099/13500872-141-11-2977

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We examined the role of plasmid-based phage defence in maintaining plasmids, using colicin plasmids in Escherichia coli as a model system. Experimental data indicated that the possession of a colicin plasmid can confer limited protection against bacteriophages. A continuous culture model, using these experimental values, indicated that the observed limited protection alone could selectively maintain colicin plasmids, without requiring a competitive advantage due to colicinogeny. Phage defence might explain the current maintenance of colicin plasmids, given the naturally occurring high levels of resistance to colicins. This model also suggests that many plasmids might be maintained in natural populations, in part, by phage resistance, including 'cryptic' plasmids for which no phenotype is known.

引用

页码：2977 / 2984

页数：8

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[11] IDENTIFICATION OF CELL-WALL ANTIGENS ASSOCIATED WITH A LARGE CONJUGATIVE PLASMID ENCODING PHAGE RESISTANCE AND LACTOSE FERMENTATION ABILITY IN LACTIC STREPTOCOCCI [J].