INFECTION OF GNOTOBIOTIC PIGS WITH AN ESCHERICHIA-COLI O157-H7 STRAIN ASSOCIATED WITH AN OUTBREAK OF HEMORRHAGIC COLITIS

被引：124

作者：

FRANCIS, DH ^{[1
]}

COLLINS, JE ^{[1
]}

DUIMSTRA, JR ^{[1
]}

机构：

[1] S DAKOTA STATE UNIV, DEPT VET SCI, BROOKINGS, SD 57007 USA

来源：

INFECTION AND IMMUNITY | 1986年 / 51卷 / 03期

关键词：

D O I：

10.1128/IAI.51.3.953-956.1986

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Gnotobiotic pigs inoculated with an Escherichia coli O157:H7 strain isolated from a human with hemorrhagic colitis developed anorexia, lethargy, and watery diarrhea. Bacteria diffusely colonized the cecum and colon surfaces and the crypt epithelium. At bacterial attachment sites, microvilli were effaced, and epithelial cells were irregularly shaped, rounded, or detached. Submucosa, lamina propria, and mesentery were markedly edematous and contained many inflammatory cells.

引用

页码：953 / 956

页数：4

共 14 条

[1] COLONIZATION OF CHICKEN CECAE BY ESCHERICHIA-COLI ASSOCIATED WITH HEMORRHAGIC COLITIS
BEERY, JT
DOYLE, MP
SCHOENI, JL
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1985, 49 (02) : 310 - 315
[2] SPORADIC CASES OF HEMOLYTIC-UREMIC SYNDROME ASSOCIATED WITH FECAL CYTO-TOXIN AND CYTOTOXIN-PRODUCING ESCHERICHIA-COLI IN STOOLS
KARMALI, MA
PETRIC, M
STEELE, BT
LIM, C
[J]. LANCET, 1983, 1 (8325) : 619 - 620
[3] KARNOVSKY MJ, 1965, J CELL BIOL, V27, pA137
[4] MODIFIED THIOCARBOHYDRAZIDE PROCEDURE FOR SCANNING ELECTRON-MICROSCOPY - ROUTINE USE FOR NORMAL, PATHOLOGICAL, OR EXPERIMENTAL TISSUES
MALICK, LE
WILSON, RB
STETSON, D
[J]. STAIN TECHNOLOGY, 1975, 50 (04): : 265 - 269
[5] RAPID CHEMICAL DEHYDRATION OF BIOLOGIC SAMPLES FOR SCANNING ELECTRON-MICROSCOPY USING 2,2-DIMETHOXYPROPANE
MASER, MD
TRIMBLE, JJ
[J]. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1977, 25 (04) : 247 - 251
[6] ATTACHING AND EFFACING ACTIVITIES OF RABBIT AND HUMAN ENTEROPATHOGENIC ESCHERICHIA-COLI IN PIG AND RABBIT INTESTINES
MOON, HW
WHIPP, SC
ARGENZIO, RA
LEVINE, MM
GIANNELLA, RA
[J]. INFECTION AND IMMUNITY, 1983, 41 (03) : 1340 - 1351
[7] PRODUCTION OF SHIGELLA-DYSENTERIAE TYPE-1-LIKE CYTO-TOXIN BY ESCHERICHIA-COLI
OBRIEN, AD
LAVECK, GD
THOMPSON, MR
FORMAL, SB
[J]. JOURNAL OF INFECTIOUS DISEASES, 1982, 146 (06) : 763 - 769
[8] SPORADIC CASES OF HEMORRHAGIC COLITIS ASSOCIATED WITH ESCHERICHIA-COLI O157-H7 - CLINICAL, EPIDEMIOLOGIC, AND BACTERIOLOGIC FEATURES
PAI, CH
GORDON, R
SIMS, HV
BRYAN, LE
[J]. ANNALS OF INTERNAL MEDICINE, 1984, 101 (06) : 738 - 742
[9] SPORADIC CASES OF HEMORRHAGIC COLITIS ASSOCIATED WITH ESCHERICHIA-COLI O157-H7
REMIS, RS
MACDONALD, KL
RILEY, LW
PUHR, ND
WELLS, JG
DAVIS, BR
BLAKE, PA
COHEN, ML
[J]. ANNALS OF INTERNAL MEDICINE, 1984, 101 (05) : 624 - 626
[10] HEMORRHAGIC COLITIS ASSOCIATED WITH A RARE ESCHERICHIA-COLI SEROTYPE
RILEY, LW
REMIS, RS
HELGERSON, SD
MCGEE, HB
WELLS, JG
DAVIS, BR
HEBERT, RJ
OLCOTT, ES
JOHNSON, LM
HARGRETT, NT
BLAKE, PA
COHEN, ML
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1983, 308 (12) : 681 - 685

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