RELATION OF URINARY COTININE CONCENTRATIONS TO CIGARETTE-SMOKING AND TO EXPOSURE TO OTHER PEOPLES SMOKE

被引:63
作者
THOMPSON, SG [1 ]
STONE, R [1 ]
NANCHAHAL, K [1 ]
WALD, NJ [1 ]
机构
[1] ST BARTHOLOMEWS HOSP,COLL MED,DEPT ENVIRONM & PREVENT MED,EPIDEMIOL RES GRP,LONDON EC1A 7BE,ENGLAND
关键词
D O I
10.1136/thx.45.5.356
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The relation of urinary cotinine measurements to tobacco consumption in smokers and to exposure to other people's smoke in non-smokers was studied in 49 smokers and 184 reported non-smokers attending a health screening centre. The median urinary cotinine concentration was 1623 ng/ml in the smokers and 6.1 ng/ml in the non-smokers. In smokers the average urinary cotinine concentration increased with reported habitual cigarette consumption; in non-smokers it increased with the reported total seven day duration of exposure to other people's tobacco smoke. Cotinine concentrations were approximately three times higher in non-smokers living with a spouse or partner who was a smoker than in those living with a non-smoker; their reported duration of exposure to tobacco smoke was also three times higher. Non-smoking subjects who were exposed to any tobacco smoke and who lived with a smoker reported 70% of their exposure to be at home (56% for men and 86% for women); the men reported more exposure at work than non-smoking men who lived with a non-smoker. This study confirms the relation of urinary cotinine to stated tobacco smoke exposure in both smokers and non-smokers and further validates the use of information on the smoking habits of the spouse or partner as a measure of tobacco smoke exposure in epidemiological studies of non-smokers.
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页码:356 / 361
页数:6
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