SYNTHESIS AND NUCLEASE ACTIVITY OF SOME PORPHYRIN ACRIDONE HYBRID MOLECULES

被引：18

作者：

MEHTA, G ^{[1
]}

SAMBAIAH, T ^{[1
]}

MAIYA, BG ^{[1
]}

SIRISH, M ^{[1
]}

CHATTERJEE, D ^{[1
]}

机构：

[1] CTR CELLULAR & MOLEC BIOL,HYDERABAD 500007,INDIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 22期

关键词：

D O I：

10.1039/p19930002667

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short synthesis of several 'porphyrin-acridone' hybrids 4a-e based on 5-(4-hydroxyphenyl)-10,15,20-tris(p-tolyl)porphyrin 1 and observations on their photoinitiated nuclease activity are reported.

引用

页码：2667 / 2669

页数：3

共 12 条

[1] EFFECT OF LINKER LENGTH ON DNA-BINDING AFFINITY, CROSS-LINKING EFFICIENCY AND CYTOTOXICITY OF C8-LINKED PYRROLOBENZODIAZEPINE DIMERS [J].

BOSE, DS ;

THOMPSON, AS ;

SMELLIE, M ;

BERARDINI, MD ;

HARTLEY, JA ;

JENKINS, TC ;

NEIDLE, S ;

THURSTON, DE .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1992, (20) :1518-1520

[2]

DORR RT, 1989, CANCER RES, V49, P340

[3]

ESTEMADMOGHADAM G, 1989, TETRAHEDRON, V45, P2641

[4] INVITRO AND INVIVO ACTIVITIES OF ATALAPHILLININE AND RELATED ACRIDONE ALKALOIDS AGAINST RODENT MALARIA [J].

FUJIOKA, H ;

NISHIYAMA, Y ;

FURUKAWA, H ;

KUMADA, N .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (01) :6-9

[5]

GALY JP, 1979, SYNTHESIS-STUTTGART, P944

[6] QUANTUM YIELD OF SINGLET OXYGEN PRODUCTION BY XANTHENE DERIVATIVES [J].

GANDIN, E ;

LION, Y ;

VANDEVORST, A .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1983, 37 (03) :271-278

[7]

Henderson B., 1992, PHOTODYNAMIC THERAPY

[8] SYNTHESIS OF SOME SUBSTITUTED TETRAARYLPORPHYRINS [J].

LITTLE, RG ;

ANTON, JA ;

LOACH, PA ;

IBERS, JA .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1975, 12 (02) :343-349

[9] SYNTHESIS OF COVALENTLY LINKED TETRA-ARYL-PORPHYRIN DIMERS [J].

LITTLE, RG .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1978, 15 (02) :203-208

[10] BLEOMYCIN MODELS - HEMIN ACRIDINES WHICH BIND TO DNA AND CAUSE OXYGEN-DEPENDENT SCISSION [J].

LOWN, JW ;

JOSHUA, AV .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, (22) :1298-1300

← 1 2 →