SLEEP DEPRIVATION-INDUCED NEURONAL DAMAGE MAY BE DUE TO NICOTINIC-ACID DEPLETION

被引：6

作者：

REIMUND, E

机构：

[1] Department of Pathology, Tulane University School of Medicine, New Orleans, LA 70112

来源：

MEDICAL HYPOTHESES | 1991年 / 34卷 / 03期

关键词：

D O I：

10.1016/0306-9877(91)90224-M

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Prolonged sleep deprivation induces chromatolysis of central nervous system neurons. This unusual form of neuronal damage is curiously similar to the neuronal damage seen in pellagra. It is proposed that the neuronal damage of prolonged sleep deprivation is a consequence of nicotinic acid depletion.

引用

页码：275 / 277

页数：3

共 6 条

[1] Studies in experimental exhaustion due to lack of sleep IV. Effects on the nerve cells in the medulla [J].