PRODUCTION OF BASIC FIBROBLAST GROWTH-FACTOR IN CULTURED RAT-BRAIN MICROGLIA

被引：111

作者：

SHIMOJO, M ^{[1
]}

NAKAJIMA, K ^{[1
]}

TAKEI, N ^{[1
]}

HAMANOUE, M ^{[1
]}

KOHSAKA, S ^{[1
]}

机构：

[1] NATL INST NEUROSCI, DEPT NEUROCHEM, 4-1-1 OGAWA HIGASHI, KODAIRA, TOKYO 187, JAPAN

来源：

NEUROSCIENCE LETTERS | 1991年 / 123卷 / 02期

关键词：

BASIC FIBROBLAST GROWTH FACTOR; MICROGLIA;

D O I：

10.1016/0304-3940(91)90937-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The production of basic fibroblast growth factor (bFGF) in cultured rat brain microglia was investigated. Rat brain microglia were found to express mRNA of bFGF in analysis by polymerase chain reaction (PCR) technique. Basic FGF was also detected in microglial cell lysate by Western blot analysis. These results indicate that microglia produce bFGF and possibly contribute to the regulation of neuronal development and regeneration.

引用

页码：229 / 231

页数：3

共 27 条

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