BACILLUS CALMETTE-GUERIN THERAPY FOR SUPERFICIAL BLADDER-CANCER - A 10-YEAR FOLLOW-UP

被引：150

作者：

HERR, HW ^{[1
]}

WARTINGER, DD ^{[1
]}

FAIR, WR ^{[1
]}

OETTGEN, HF ^{[1
]}

机构：

[1] MEM SLOAN KETTERING CANC CTR,DEPT MED,CLIN IMMUNOL SERV,NEW YORK,NY 10021

来源：

JOURNAL OF UROLOGY | 1992年 / 147卷 / 04期

关键词：

BLADDER NEOPLASMS; BCG VACCINE; CARCINOMA; TRANSITIONAL CELL;

D O I：

10.1016/S0022-5347(17)37452-9

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report the outcome of 61 patients with superficial bladder tumors who received bacillus Calmette-Guerin (BCG) therapy and were followed for at least 10 years (range 10 to 13 years). A total of 19 patients (31%) remains free of tumor and progression, 17 (28%) had interval superficial recurrences but no progression and 25 (41%) had progression, first identified as muscle invasion in 12, prostatic involvement in 8 or metastasis in 5. Most tumors recurred or progressed within the first 5 years. Of the 61 patients 33 (54%) are disease-free and with an intact bladder, 13 (21%) are alive after cystectomy, 2 (3%) died of other causes, 1 (2%) is alive with metastasis and 12 (20%) died of metastatic urothelial cancer (11 from the bladder or prostate and 1 from an upper tract tumor).

引用

页码：1020 / 1023

页数：4

共 6 条

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LAUDONE, VP ;

BADALAMENT, RA ;

OETTGEN, HF ;

SOGANI, PC ;

FREEDMAN, BD ;

MELAMED, MR ;

WHITMORE, WF .

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[3]

2-Z

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[5]

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