LONGAMIDE AND 3,7-DIMETHYLISOGUANINE, 2 NOVEL ALKALOIDS FROM THE MARINE SPONGE AGELAS-LONGISSIMA

被引：77

作者：

CAFIERI, F ^{[1
]}

FATTORUSSO, E ^{[1
]}

MANGONI, A ^{[1
]}

TAGLIALATELASCAFATI, O ^{[1
]}

机构：

[1] DIPARTIMENTO CHIM SOSTANZE NAT, I-80131 NAPLES, ITALY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 43期

关键词：

D O I：

10.1016/0040-4039(95)01626-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A purine derivative, 3,7-dimethylisoguanine (1), and a novel alkaloid with the unusual pyrrolopiperazine nucleus, longamide (2), were isolated from the sponge Agelas longissima, and their structures established on the basis of spectroscopic data. In addition, 2 exhibited a mild antibacterial activity.

引用

页码：7893 / 7896

页数：4

共 14 条

[1] ZUR KONSTITUTION DES ZOOANEMONINS UND DES HERBIPOLINS
ACKERMANN, D
LIST, PH
[J]. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1960, 318 : 281 - 281
[2] CAFIERI F, 1994, LIEBIGS ANN CHEM, P1187
[3] CAFIERI F, IN PRESS LIEBIGS ANN
[4] CAFIERI F, 1995, BIOMED CHEM LETT, V8, P799
[5] ANTIMICROBIAL METABOLITES FROM A PACIFIC SPONGE, AGELAS SP
CAPON, RJ
FAULKNER, DJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (06) : 1819 - 1822
[6] NEW BROMO-PYRROLE DERIVATIVES FROM SPONGE AGELAS-OROIDES
FORENZA, S
MINALE, L
RICCIO, R
[J]. JOURNAL OF THE CHEMICAL SOCIETY D-CHEMICAL COMMUNICATIONS, 1971, (18): : 1129 - &
[7] REINVESTIGATION INTO STRUCTURE OF OROIDIN, A BROMOPYRROLE DERIVATIVE FROM MARINE SPONGE
GARCIA, EE
BENJAMIN, LE
FRYER, RI
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1973, (03) : 78 - 79
[8] Jaffe H. H., 1962, THEORY APPL UV SPECT, P350
[9] KAZIMIERCZUK Z, 1974, ACTA BIOCHIM POL, V21, P455
[10] A NOVEL ANTAGONIST OF SEROTONERGIC RECEPTORS, HYMENIDIN, ISOLATED FROM THE OKINAWAN MARINE SPONGE HYMENIACIDON SP
KOBAYASHI, J
OHIZUMI, Y
NAKAMURA, H
HIRATA, Y
[J]. EXPERIENTIA, 1986, 42 (10): : 1176 - 1177

← 1 2 →