2,3-DIHYDRO-3-(1-PYRRYL)SPIRO[BENZOFURAN-2,4'-PIPERIDINE]S AND 2,3-DIHYDRO-3-(1-PYRRYL)SPIRO[BENZOFURAN-2,3'-PYRROLIDINE]S - NOVEL ANTIHYPERTENSIVE AGENTS

被引：9

作者：

DAVIS, L ^{[1
]}

AGNEW, MN ^{[1
]}

EFFLAND, RC ^{[1
]}

KLEIN, JT ^{[1
]}

KITZEN, JM ^{[1
]}

SCHWENKLER, MA ^{[1
]}

机构：

[1] HOECHST ROUSSEL PHARMACEUT INC,DEPT BIOL SCI,SOMERVILLE,NJ 08876

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1983年 / 26卷 / 10期

关键词：

D O I：

10.1021/jm00364a027

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1505 / 1510

页数：6

共 14 条

[1]

ALLEN RC, 1978, J MED CHEM, V21, P1149

[2] SYNTHESIS OF SPIRO[ISOBENZOFURAN-1(3H),4'-PIPERIDINES]AS POTENTIAL CENTRAL NERVOUS-SYSTEM AGENTS .1. [J].

BAUER, VJ ;

DUFFY, BJ ;

HOFFMAN, D ;

KLIOZE, SS ;

KOSLEY, RW ;

MCFADDEN, AR ;

MARTIN, LL ;

ONG, HH ;

GEYER, HM .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (11) :1315-1324

[3]

BUGGY J, 1977, CIRC RES, V40, P110

[4] SYNTHESIS OF 2,3-DIHYDROSPIRO[BENZOFURAN-2,4'-PIPERIDINES] AND 2,3-DIHYDROSPIRO[BENZOFURAN-2,3'-PYRROLIDINES] [J].

EFFLAND, RC ;

GARDNER, BA ;

STRUPCZEWSKI, J .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1981, 18 (04) :811-814

[5]

GROOLMAN A, 1944, P SOC EXP BIOL MED, V57, P102

[6]

JACKMAN LM, 1969, APPLICATIONS NUCLEAR, V5, P94

[7] BENZENESULFENAMIDES AS ANTIHYPERTENSIVE AGENTS - SUBSTITUTED PIPERIDINE AND 1-ARYLPIPERAZINE DERIVATIVES [J].

KLIOZE, SS ;

ALLEN, RC ;

WILKER, JC ;

WOODWARD, DL .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (06) :677-679

[8] SPIRO[ISOBENZOFURAN-1(3H),4'-PIPERIDINES] .3. DIURETIC AND ANTIHYPERTENSIVE PROPERTIES OF COMPOUNDS CONTAINING A SULFUR ATTACHED TO NITROGEN [J].

KLIOZE, SS ;

NOVICK, WJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (04) :400-403

[9]

LEVY GC, 1972, CARBON 13 NUCLEAR MA, P24

[10]

SADTLER IH, 1973, J CHEM SOC CHEM COMM, P809

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