IMMUNOLOCALIZATION OF BASEMENT-MEMBRANE MOLECULES IN THE STROMA OF SALIVARY-GLAND PLEOMORPHIC ADENOMA

被引：44

作者：

SAKU, T ^{[1
]}

CHENG, J ^{[1
]}

OKABE, H ^{[1
]}

KOYAMA, Z ^{[1
]}

机构：

[1] NAGASAKI UNIV,SCH DENT,DEPT PROSTHODONT,NAGASAKI 852,JAPAN

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1990年 / 19卷 / 05期

关键词：

basement membranes; entactin; heparan sulfate proteoglycan; immunohistochemistry; laminin; pleomorphic adenoma; type IV collagen;

D O I：

10.1111/j.1600-0714.1990.tb00827.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

In order to determine the participation of basement membrane molecules in formation of its characteristic stroma, 30 cases of salivary gland pleomorphic adenoma were examined by immunohistochemical staining for type IV collagen, laminin, heparan sulfate proteoglycan, and entactin. The stroma was histopathologically classified into four types: hyaline, fibrous, myxoid, and chondroid. Immunohistochemically, type IV collagen and laminin were more intensively localized in hyaline, fibrous and chondroid types of stroma, whereas heparan sulfate proteoglycan was more prominent in myxoid areas. The results suggest that the stroma contains these basement membrane components, which are possibly bio‐synthesized by epithelial tumor cells, and that histological variety of the stroma depends on proportion of local contents of each basement membrane molecule. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：208 / 214

页数：7

共 29 条

[1] SALIVARY GLAND TUMOURS AND THEIR MUCINS [J].

AZZOPARDI, JG ;

SMITH, OD .

JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1959, 77 (01) :131-&

[2] BASAL LAMINA OF EMBRYONIC SALIVARY EPITHELIA - PRODUCTION BY EPITHELIUM AND ROLE IN MAINTAINING LOBULAR MORPHOLOGY [J].

BANERJEE, SD ;

COHN, RH ;

BERNFIELD, MR .

JOURNAL OF CELL BIOLOGY, 1977, 73 (02) :445-463

[3]

CHENG J, 1990, IN PRESS AM J PATHOL, V136

[4] FIBRONECTIN AND TYPE-III COLLAGEN IN EPITHELIAL NEOPLASMS OF GASTROINTESTINAL-TRACT AND SALIVARY-GLAND [J].

DARDENNE, AJ ;

BURNS, J ;

SYKES, BC ;

BENNETT, MK .

JOURNAL OF CLINICAL PATHOLOGY, 1983, 36 (07) :756-763

[5] PLEOMORPHIC ADENOMA .2. ULTRASTRUCTURAL ORGANIZATION OF STROMAL REGIONS [J].

DARDICK, I ;

VANNOSTRAND, AWP ;

JEANS, MTD ;

RIPPSTEIN, P ;

EDWARDS, V .

HUMAN PATHOLOGY, 1983, 14 (09) :798-809

[6] HISTOGENESIS OF SALIVARY-GLAND PLEOMORPHIC ADENOMA (MIXED TUMOR) WITH AN EVALUATION OF THE ROLE OF THE MYOEPITHELIAL CELL [J].

DARDICK, I ;

VANNOSTRAND, AWP ;

PHILLIPS, MJ .

HUMAN PATHOLOGY, 1982, 13 (01) :62-75

[7]

DEPPISCH LM, 1969, CANCER, V24, P174, DOI 10.1002/1097-0142(196907)24:1<174::AID-CNCR2820240122>3.0.CO

[8]

2-X

[9]

DOYLE LE, 1968, CANCER, V22, P225, DOI 10.1002/1097-0142(196807)22:1<225::AID-CNCR2820220126>3.0.CO

[10]

2-X

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