COMBINED EFFECTS OF HEAT-TREATMENT AND PLASTICIZERS ON POLYVINYL-ALCOHOL FILMS

被引：7

作者：

LIM, LY

WAN, LSC

机构：

[1] Department of Pharmacy, National University of Singapore 10

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1995年 / 21卷 / 03期

关键词：

D O I：

10.3109/03639049509048117

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The effects of heat treatment on PVA films containing water soluble plasticizers were investigated. Propylene glycol, glycerol and polyethylene glycol were used as plasticizers. There was synergism between heat treatment and the presence of plasticizers in enhancing the water resistance of PVA films. In the absence of heat treatment, however, the plasticizers increased the aqueous solubility of PVA films. The plasticized films further showed a lower permeability to propranolol HCl compared to the unplasticized films following heat treatment.

引用

页码：369 / 373

页数：5

共 5 条

[1] DIFFUSIVE PERMEABILITY OF SOLUTES IN POLYVINYL-ALCOHOL) MEMBRANES AS A FUNCTION OF THE DEGREE OF HYDRATION [J].