CHROMOPHORE-ENHANCED LASER-TUMOR TISSUE PHOTOTHERMAL INTERACTION USING AN 808-NM DIODE-LASER

被引：152

作者：

CHEN, WR

ADAMS, RL

HEATON, S

DICKEY, DT

BARTELS, KE

NORDQUIST, RE

机构：

[1] UNIV OKLAHOMA,DEPT PHYS & ASTRON,NORMAN,OK 73109

[2] DEAN A MCGEE EYE INST,OKLAHOMA CITY,OK 73104

[3] OKLAHOMA STATE UNIV,COLL VET MED,DEPT MED & SURG,STILLWATER,OK 74078

[4] OKLAHOMA STATE UNIV,CTR LASER RES,STILLWATER,OK 74078

来源：

CANCER LETTERS | 1995年 / 88卷 / 01期

关键词：

CHROMOPHORE; 808-NM DIODE LASER; INDOCYANINE GREEN; PHOTOTHERMAL EFFECT; CANCER TREATMENT;

D O I：

10.1016/0304-3835(94)03609-M

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A diode laser was used to irradiate tumor tissue, with indocyanine green as the chromophore. The 808-nm wavelength radiation falls within the absorption peak of the chromophore (about 780 nm). The preliminary results in this report revealed clear and significant coupling of this laser and indocyanine green in laser-tissue photothermal interaction. The chromophore targeted tissue showed laser damage while peripheral tissues remained intact. Without the chromophore, this laser inflicted no apparent tissue damage in the non-contact mode with irradiance up to 1755 J/cm(2).

引用

页码：15 / 19

页数：5

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