TRISOMY-19 IN A PATIENT WITH MYELODYSPLASTIC SYNDROME AND THROMBOCYTOSIS

被引：5

作者：

HUMPHRIES, JE

WHEBY, MS

机构：

[1] Division of Hematology/Oncology, Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville

来源：

CANCER GENETICS AND CYTOGENETICS | 1990年 / 44卷 / 02期

关键词：

D O I：

10.1016/0165-4608(90)90045-C

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient with refractory anemia with excess blasts, ringed sideroblasts, and thrombocytosis was found on cytogenetic analysis to have trisomy 19 as the sole abnormality. Although trisomy 19 in combination with other chromosomal anomalies has been encountered in association with a variety of hematologic malignancies, many solid tumors, and the myelodysplastic syndrome, its occurrence as the only cytogenetic aberration is rare and has not been reported in association with thrombocythemia. © 1990.

引用

页码：187 / 191

页数：5

共 35 条

[1] THE PROGNOSTIC VALUE OF CHROMOSOME-STUDIES IN PATIENTS WITH THE PRELEUKEMIC SYNDROME (HEMATOPOIETIC DYSPLASIA)
ANDERSON, RL
BAGBY, GC
[J]. LEUKEMIA RESEARCH, 1982, 6 (02) : 175 - 181
[2] ANDREWS RG, 1983, BLOOD, V62, P124
[3] CYTOGENETIC STUDY OF 88 CASES OF REFRACTORY-ANEMIA
AYRAUD, N
DONZEAU, M
RAYNAUD, S
LAMBERT, JC
[J]. CANCER GENETICS AND CYTOGENETICS, 1983, 8 (03) : 243 - 248
[4] BENEDICT WF, 1979, BLOOD, V54, P818
[5] CHEN H, 1981, ANN GENET-PARIS, V24, P32
[6] A MONOCLONAL-ANTIBODY REACTIVE WITH NORMAL AND LEUKEMIC HUMAN MYELOID PROGENITOR CELLS
GRIFFIN, JD
LINCH, D
SABBATH, K
LARCOM, P
SCHLOSSMAN, SF
[J]. LEUKEMIA RESEARCH, 1984, 8 (04) : 521 - 534
[7] ACUTE-LEUKEMIA AND THE SAME CHROMOSOME ABNORMALITY IN MONOZYGOTIC TWINS
HARTLEY, SE
SAINSBURY, C
[J]. HUMAN GENETICS, 1981, 58 (04) : 408 - 410
[8] MYELODYSPLASTIC SYNDROMES - PATHOGENESIS, FUNCTIONAL ABNORMALITIES, AND CLINICAL IMPLICATIONS
JACOBS, A
[J]. JOURNAL OF CLINICAL PATHOLOGY, 1985, 38 (11) : 1201 - 1217
[9] KARDON N, 1982, CANCER, V50, P2834, DOI 10.1002/1097-0142(19821215)50:12<2834::AID-CNCR2820501224>3.0.CO
[10] 2-H

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