DETERMINATION OF (+)-NILVADIPINE AND (-)-NILVADIPINE IN HUMAN-PLASMA USING CHIRAL STATIONARY-PHASE LIQUID-CHROMATOGRAPHY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY, AND A PRELIMINARY PHARMACOKINETIC STUDY IN HUMANS

被引：50

作者：

TOKUMA, Y

FUJIWARA, T

NOGUCHI, H

机构：

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1987年 / 76卷 / 04期

关键词：

D O I：

10.1002/jps.2600760410

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：310 / 313

页数：4

共 25 条

[1] CHIRAL STATIONARY PHASES FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS - A MINI-REVIEW [J].

ARMSTRONG, DW .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1984, 7 :353-376

[2] DETERMINATION OF BETAXOLOL ENANTIOMERS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - APPLICATION TO PHARMACOKINETIC STUDIES [J].

DARMON, A ;

THENOT, JP .

JOURNAL OF CHROMATOGRAPHY, 1986, 374 (02) :321-328

[3] DIFFERENTIAL STEREOSELECTIVE METABOLISM OF METOPROLOL IN EXTENSIVE AND POOR DEBRISOQUIN METABOLIZERS [J].

LENNARD, MS ;

TUCKER, GT ;

SILAS, JH ;

FREESTONE, S ;

RAMSAY, LE ;

WOODS, HF .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1983, 34 (06) :732-737

[4] CHROMATOGRAPHIC RESOLUTION OF ENANTIOMERS - SELECTIVE REVIEW [J].

LOCHMULLER, CH ;

SOUTER, RW .

JOURNAL OF CHROMATOGRAPHY, 1975, 113 (03) :283-302

[5] DETERMINATION OF FLURAZEPAM IN HUMAN-PLASMA BY GAS CHROMATOGRAPHY-ELECTRON CAPTURE NEGATIVE CHEMICAL IONIZATION MASS-SPECTROMETRY [J].

MIWA, BJ ;

GARLAND, WA ;

BLUMENTHAL, P .

ANALYTICAL CHEMISTRY, 1981, 53 (06) :793-797

[6] STUDIES ON A NEW 1,5-BENZOTHIAZEPINE DERIVATIVE (CRD-401) .2. VASODILATOR ACTIONS [J].

NAGAO, T ;

SATO, M ;

NAKAJIMA, H ;

KIYOMOTO, A .

JAPANESE JOURNAL OF PHARMACOLOGY, 1972, 22 (01) :1-&

[7] COMPARISON OF THE CARDIOVASCULAR EFFECT OF FR34235, A NEW DIHYDROPYRIDINE, WITH OTHER CALCIUM-ANTAGONISTS [J].

OHTSUKA, M ;

ONO, T ;

HIROI, J ;

ESUMI, K ;

KIKUCHI, H ;

KUMADA, S .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1983, 5 (06) :1074-1082

[8]

OHTSUKA M, UNPUB

[9] CHROMATOGRAPHIC RESOLUTION .4. NOVEL PACKING MATERIAL FOR OPTICAL RESOLUTION - (+)-POLY(TRIPHENYLMETHYL METHACRYLATE) COATED ON MACROPOROUS SILICA-GEL [J].

OKAMOTO, Y ;

HONDA, S ;

OKAMOTO, I ;

YUKI, H ;

MURATA, S ;

NOYORI, R ;

TAKAYA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (23) :6971-6973

[10] DIRECT LIQUID-CHROMATOGRAPHIC SEPARATION OF BENZODIAZEPINONE ENANTIOMERS [J].

PIRKLE, WH ;

TSIPOURAS, A .

JOURNAL OF CHROMATOGRAPHY, 1984, 291 (MAY) :291-298

← 1 2 3 →