PROTEIN DESIGN - NOVEL METAL-BINDING SITES

被引：150

作者：

REGAN, L

机构：

[1] Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, CT 06520

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 07期

关键词：

D O I：

10.1016/S0968-0004(00)89044-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In natural proteins, metal ions play a variety of roles, including nucleophilic catalysis, electron transfer and the stabilization of protein structure. The de novo design of metal-binding sites is therefore an attractive means by which to impart proteins with novel properties and activities.

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页码：280 / 285

页数：6

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