LOCALIZATION OF THE GENE-ENCODING UPSTREAM STIMULATORY FACTOR (USF) TO HUMAN CHROMOSOME-1Q22-Q23

被引：22

作者：

SHIEH, BH

SPARKES, RS

GAYNOR, RB

LUSIS, AJ

机构：

[1] UNIV CALIF LOS ANGELES,DEPT MICROBIOL & MOLEC GENET,LOS ANGELES,CA 90024

[2] UNIV TEXAS,HLTH SCI CTR,SW MED SCH,DEPT MED,DALLAS,TX 75235

[3] UNIV TEXAS,HLTH SCI CTR,SW MED SCH,DEPT MICROBIOL,DALLAS,TX 75235

[4] UNIV CALIF LOS ANGELES,DEPT MED,LOS ANGELES,CA 90024

来源：

GENOMICS | 1993年 / 16卷 / 01期

关键词：

D O I：

10.1006/geno.1993.1174

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The upstream stimulatory factor, USF, is a ubiquitously expressed cellular transcription factor that binds to a symetrical DNA sequence that is found in a variety of viral and cellular promoters. A full-length cDNA encoding the 43-kDa USF protein has previously been isolated. USF contains both helix-loop-helix and leucine repeats, which are involved in regulating its DNA binding and dimerization properties. We report the use of mouse-human somatic cell hybrids and in situ hybridization in localizing the gene-encoding USF to human chromosome 1q22-q23. © 1993 Academic Press, Inc.

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页码：266 / 268

页数：3

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