CALCIUM-DEPENDENT POSTSYNAPTIC EXOCYTOSIS - A POSSIBLE MECHANISM FOR ACTIVITY-DEPENDENT SYNAPTIC MODULATION

被引：12

作者：

DAN, Y ^{[1
]}

POO, MM ^{[1
]}

机构：

[1] COLUMBIA UNIV,DEPT BIOL SCI,NEW YORK,NY 10027

来源：

JOURNAL OF NEUROBIOLOGY | 1994年 / 25卷 / 03期

关键词：

SYNAPTIC PLASTICITY; NEUROMUSCULAR JUNCTION; RETROGRADE INTERACTION; EXOCYTOSIS; QUANTAL SECRETION;

D O I：

10.1002/neu.480250313

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Elevation of cytosolic Ca2+ level in the postsynaptic cell is critical for the induction of many forms of activity-dependent synaptic modulation. Based on our recent evidence that in muscle cells and fibroblasts constitutive exocytosis is increased by elevating cytosolic Ca2+ levels, we hypothesize that Ca2+-dependent exocytosis at the postsynaptic site may provide a mechanism for a localized, activity-dependent synaptic modulation. (C) 1994 John Wiley and Sons, Inc.

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页码：336 / 341

页数：6

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