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TOTAL SYNTHESIS OF (+)-POLYOXIN-J STARTING FROM MYOINOSITOL

被引：71
作者：
CHIDA, N
KOIZUMI, K
KITADA, Y
YOKOYAMA, C
OGAWA, S
机构：
来源：
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 01期
关键词：
D O I：
10.1039/c39940000111
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The total synthesis of the antifungal antibiotic, polyoxin J 1 starting from myo-inositol is described; the two key components, 2 and 3, were prepared from a pair of optically resolved myo-inositol derivatives 4L and 4D, respectively, using a highly regioselective Baeyer-Villiger reaction, and finally coupled to complete the total synthesis.
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页码：111 / 113
页数：3
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