CONFORMATIONAL AND DYNAMIC CONSIDERATIONS IN THE DESIGN OF PEPTIDE-HORMONE ANALOGS

被引：23

作者：

HRUBY, VJ

MOSBERG, HI

SAWYER, TK

KNITTEL, JJ

ROCKWAY, TW

ORMBERG, J

DARMAN, P

CHAN, WY

HADLEY, ME

机构：

[1] UNIV ARIZONA,DEPT BIOCHEM,TUCSON,AZ 85721

[2] CORNELL UNIV,MED CTR,COLL MED,DEPT PHARMACOL,NEW YORK,NY 10021

[3] UNIV ARIZONA,DEPT GEN BIOL,TUCSON,AZ 85721

来源：

BIOPOLYMERS | 1983年 / 22卷 / 01期

关键词：

D O I：

10.1002/bip.360220165

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：517 / 530

页数：14

共 41 条

[1] RACEMIZATION EFFECTS ON MELANOCYTE-STIMULATING HORMONES AND RELATED PEPTIDES [J].

BOOL, AM ;

GRAY, GH ;

HADLEY, ME ;

HEWARD, CB ;

HRUBY, VJ ;

SAWYER, TK ;

YANG, YCS .

JOURNAL OF ENDOCRINOLOGY, 1981, 88 (01) :57-65

[2] C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF OXYTOCIN, RELATED OLIGOPEPTIDES, AND SELECTED ANALOGS [J].

BREWSTER, AI ;

HRUBY, VJ ;

SPATOLA, AF ;

BOVEY, FA .

BIOCHEMISTRY, 1973, 12 (08) :1643-1649

[3] CONFORMATION OF LL AND LD HAIRPIN BENDS WITH INTERNAL HYDROGEN-BONDS IN PROTEINS AND PEPTIDES [J].

CHANDRASEKARAN, R ;

LAKSHMINARAYANAN, AV ;

PANDYA, UV ;

RAMACHANDRAN, GN .

BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 303 (01) :14-27

[4] EMPIRICAL PREDICTIONS OF PROTEIN CONFORMATION [J].

CHOU, PY ;

FASMAN, GD .

ANNUAL REVIEW OF BIOCHEMISTRY, 1978, 47 :251-276

[5]

EBERLE AN, 1981, PERSPECTIVES PEPTIDE, P407

[6] QUANTITATIVE-DETERMINATION OF AMINO-ACID RACEMIZATION IN HEAT-ALKALI-TREATED MELANOTROPINS - IMPLICATIONS FOR PEPTIDE-HORMONE STRUCTURE-FUNCTION STUDIES [J].

ENGEL, MH ;

SAWYER, TK ;

HADLEY, ME ;

HRUBY, VJ .

ANALYTICAL BIOCHEMISTRY, 1981, 116 (02) :303-311

[7] EFFECTS OF ALKALI-HEAT TREATMENT ON BETA-MELANOCYTE-STIMULATING HORMONE [J].

GESCHWIND, II ;

LI, CH .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1964, 106 (1-3) :200-&

[8]

GLICKSON JD, 1975, PEPTIDES CHEM STRUCT, P782

[9] CALCIUM-DEPENDENT PROLONGED EFFECTS ON MELANOPHORES OF [4-NORLEUCINE, 7-D-PHENYLALANINE]-ALPHA-MELANOTROPIN [J].

HADLEY, ME ;

ANDERSON, B ;

HEWARD, CB ;

SAWYER, TK ;

HRUBY, VJ .

SCIENCE, 1981, 213 (4511) :1025-1027

[10]

HADLEY ME, 1981, CIBA F S, V81, P242

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