TREATMENT OF STREPTOZOTOCIN-DIABETIC RATS WITH METFORMIN RESTORES THE ABILITY OF INSULIN TO INHIBIT ADENYLATE-CYCLASE ACTIVITY AND DEMONSTRATES THAT INSULIN DOES NOT EXERT THIS ACTION THROUGH THE INHIBITORY GUANINE-NUCLEOTIDE REGULATORY PROTEIN GI

被引：32

作者：

GAWLER, D

MILLIGAN, G

HOUSLAY, MD

机构：

来源：

BIOCHEMICAL JOURNAL | 1988年 / 249卷 / 02期

关键词：

D O I：

10.1042/bj2490537

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

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页码：537 / 542

页数：6

相关论文

共 56 条

[1] EFFECTS OF GUANINE-NUCLEOTIDES AND DIVALENT-CATIONS ON FORSKOLIN ACTIVATION OF RABBIT LUTEAL ADENYLYL CYCLASE - EVIDENCE FOR THE EXISTENCE OF AN INHIBITORY GUANINE NUCLEOTIDE-BINDING REGULATORY COMPONENT
ABRAMOWITZ, J
CAMPBELL, AR
[J]. ENDOCRINOLOGY, 1984, 114 (06) : 1955 - 1962
[2] CHOLERA-TOXIN DOES NOT IMPAIR HORMONAL INHIBITION OF ADENYLATE-CYCLASE AND CONCOMITANT STIMULATION OF A GTPASE IN ADIPOCYTE MEMBRANES
AKTORIES, K
SCHULTZ, G
JAKOBS, KH
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 719 (01) : 58 - 64
[3] ALFORD FP, 1986, RECENT ADV DIABETES, V2, P1
[4] BIRNBAUMER L, 1985, MOL ASPECTS CELL REG, V4, P131
[5] BLACKMORE PF, 1979, J BIOL CHEM, V254, P2828
[6] BUTCHER RW, 1966, J BIOL CHEM, V241, P1651
[7] STUDIES ON THE MECHANISM OF INSULIN RESISTANCE IN THE LIVER FROM HUMANS WITH NONINSULIN-DEPENDENT DIABETES - INSULIN ACTION AND BINDING IN ISOLATED HEPATOCYTES, INSULIN-RECEPTOR STRUCTURE, AND KINASE-ACTIVITY
CARO, JF
ITTOOP, O
PORIES, WJ
MEELHEIM, D
FLICKINGER, EG
THOMAS, F
JENQUIN, M
SILVERMAN, JF
KHAZANIE, PG
SINHA, MK
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1986, 78 (01) : 249 - 258
[8] PERTUSSIS TOXIN REVERSES GPP(NH)P INHIBITION OF BASAL AND FORSKOLIN ACTIVATED ADIPOCYTE ADENYLATE-CYCLASE
FAIN, JN
ODONNELL, CJ
MILLS, I
GARCIASAINZ, JA
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 116 (02) : 651 - 656
[9] DETECTION OF THE MAJOR PERTUSSIS TOXIN SUBSTRATE OF HUMAN-LEUKOCYTES WITH ANTISERA RAISED AGAINST SYNTHETIC PEPTIDES
FALLOON, J
MALECH, H
MILLIGAN, G
UNSON, C
KAHN, R
GOLDSMITH, P
SPIEGEL, A
[J]. FEBS LETTERS, 1986, 209 (02) : 352 - 356
[10] INSULIN STIMULATES A NOVEL GTPASE ACTIVITY IN HUMAN-PLATELETS
GAWLER, D
HOUSLAY, MD
[J]. FEBS LETTERS, 1987, 216 (01) : 94 - 98

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