MORPHOMETRIC CATEGORIZATION OF THE HUMAN OOCYTE AND EARLY CONCEPTUS

被引:27
作者
GOYANES, VJ
RONCORZO, A
COSTAS, E
MANEIRO, E
机构
[1] Unit of Human Reproduction, Clinica Ntra. Sra. de Belen
关键词
Adimensional coefficients; Human embryo; Morphometry; Volume;
D O I
10.1093/oxfordjournals.humrep.a137155
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Morphometrical procedures were used to quantitatively evaluate human oocytes and embryos in an IVF programme. The metaphase II oocyte was an irregular 3.5 × 106 μm3 sphere of 1.05 coefficient of form. The ooplasmic volume of 1.4 × 10 6 μm3 was reduced by 10% by fertilization. The zona pellucida behaved as a stable and almost spherical envelope of 1.8 × 106 /m3 volume and 17 μm thickness. Through the first three cleavages, mean blastomere reduces 28.5% volume per division, evolving from an irregular spherical shape with 0.9 coefficient of form to an ellipsoid (0.8) at the 8-cell stage. The coefficient of diversity between sister blastomeres progressively moved from 1.4 to 1.6 during the first two (2n) cleavages. The coefficient of diversity also increased at 3-cell (2.2) and 6-cell (2.6) asynchronous divisions. Morphologically abnormal embryos showed some morphometrical differences. Embryos which successfully implanted and progressed to birth showed a higher coefficient of diversity between sister blastomeres. © 1990 Oxford University Press.
引用
收藏
页码:613 / 618
页数:6
相关论文
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