CD4 ANTIGEN-BASED ANTIRECEPTOR PEPTIDES INHIBIT INFECTIVITY OF HUMAN IMMUNODEFICIENCY VIRUS INVITRO AT MULTIPLE STAGES OF THE VIRAL LIFE-CYCLE

被引：75

作者：

NARA, PL

HWANG, KM

RAUSCH, DM

LIFSON, JD

EIDEN, LE

机构：

[1] NIMH,CELL BIOL LAB,MOLEC & CELLULAR NEUROBIOL UNIT,BLDG 36,ROOM 3A-17,BETHESDA,MD 20892

[2] NCI,FREDERICK CANC RES FACIL,TUMOR CELL BIOL LAB,FREDERICK,MD 21701

[3] GENELABS INC,DIV MED BIOCHEM,REDWOOD CITY,CA 94063

[4] GENELABS INC,DIV CELLULAR IMMUNOL,REDWOOD CITY,CA 94063

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 18期

关键词：

D O I：

10.1073/pnas.86.18.7139

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：7139 / 7143

页数：5

共 20 条

[1] A SOLUBLE RECOMBINANT POLYPEPTIDE COMPRISING THE AMINO-TERMINAL HALF OF THE EXTRACELLULAR REGION OF THE CD4-MOLECULE CONTAINS AN ACTIVE BINDING-SITE FOR HUMAN IMMUNODEFICIENCY VIRUS [J].

BERGER, EA ;

FUERST, TR ;

MOSS, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (07) :2357-2361

[2] CELL-FUSION IN VIRAL DISEASES [J].

CHANY, C ;

CHANYFOURNIER, F ;

ROBAIN, O .

NATURE, 1987, 326 (6110) :250-250

[3] THE CD4 (T4) ANTIGEN IS AN ESSENTIAL COMPONENT OF THE RECEPTOR FOR THE AIDS RETROVIRUS [J].

DALGLEISH, AG ;

BEVERLEY, PCL ;

CLAPHAM, PR ;

CRAWFORD, DH ;

GREAVES, MF ;

WEISS, RA .

NATURE, 1984, 312 (5996) :763-767

[4] A SOLUBLE FORM OF CD4 (T4) PROTEIN INHIBITS AIDS VIRUS-INFECTION [J].

DEEN, KC ;

MCDOUGAL, JS ;

INACKER, R ;

FOLENAWASSERMAN, G ;

ARTHOS, J ;

ROSENBERG, J ;

MADDON, PJ ;

AXEL, R ;

SWEET, RW .

NATURE, 1988, 331 (6151) :82-84

[5] HIV INFECTION IS BLOCKED INVITRO BY RECOMBINANT SOLUBLE CD4 [J].

FISHER, RA ;

BERTONIS, JM ;

MEIER, W ;

JOHNSON, VA ;

COSTOPOULOS, DS ;

LIU, T ;

TIZARD, R ;

WALKER, BD ;

HIRSCH, MS ;

SCHOOLEY, RT ;

FLAVELL, RA .

NATURE, 1988, 331 (6151) :76-78

[6] A SOLUBLE CD4 PROTEIN SELECTIVELY INHIBITS HIV REPLICATION AND SYNCYTIUM FORMATION [J].

HUSSEY, RE ;

RICHARDSON, NE ;

KOWALSKI, M ;

BROWN, NR ;

CHANG, HC ;

SILICIANO, RF ;

DORFMAN, T ;

WALKER, B ;

SODROSKI, J ;

REINHERZ, EL .

NATURE, 1988, 331 (6151) :78-81

[7] LYMPHOCYTE-T T4 MOLECULE BEHAVES AS THE RECEPTOR FOR HUMAN RETROVIRUS LAV [J].

KLATZMANN, D ;

CHAMPAGNE, E ;

CHAMARET, S ;

GRUEST, J ;

GUETARD, D ;

HERCEND, T ;

GLUCKMAN, JC ;

MONTAGNIER, L .

NATURE, 1984, 312 (5996) :767-768

[8] SYNTHETIC CD4 PEPTIDE DERIVATIVES THAT INHIBIT HIV INFECTION AND CYTOPATHICITY [J].

LIFSON, JD ;

HWANG, KM ;

NARA, PL ;

FRASER, B ;

PADGETT, M ;

DUNLOP, NM ;

EIDEN, LE .

SCIENCE, 1988, 241 (4866) :712-716

[9] INDUCTION OF CD4-DEPENDENT CELL-FUSION BY THE HTLV-III/LAV ENVELOPE GLYCOPROTEIN [J].

LIFSON, JD ;

FEINBERG, MB ;

REYES, GR ;

RABIN, L ;

BANAPOUR, B ;

CHAKRABARTI, S ;

MOSS, B ;

WONGSTAAL, F ;

STEIMER, KS ;

ENGLEMAN, EG .

NATURE, 1986, 323 (6090) :725-728

[10] AIDS RETROVIRUS INDUCED CYTOPATHOLOGY - GIANT-CELL FORMATION AND INVOLVEMENT OF CD4 ANTIGEN [J].

LIFSON, JD ;

REYES, GR ;

MCGRATH, MS ;

STEIN, BS ;

ENGLEMAN, EG .

SCIENCE, 1986, 232 (4754) :1123-1127

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