A NEW AND CONVENIENT SYNTHESIS OF 1-AMINOCYCLOPROPANECARBOXYLIC ACID FROM CYCLOPROPANONE ACETAL

被引：25

作者：

FADEL, A

机构：

[1] Laboratoire des Carbocycles, associé au CNRS, Institut de Chimie Moléculaire d'Orsay

来源：

TETRAHEDRON | 1991年 / 47卷 / 32期

关键词：

D O I：

10.1016/S0040-4020(01)86558-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclopropanone acetal 2a undergoes the one-pot Strecker synthesis under sonication to provide the amino nitrile 8, which after hydrolysis and catalytic hydrogenolysis, gives 1-aminocyclopropanecarboxylic acid (ACC, 1) in good overall yield.

引用

页码：6265 / 6274

页数：10

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