EFFECTS OF CEFTRIAXONE ON FECAL FLORA - ANALYSIS BY MICROMORPHOMETRY

被引：8

作者：

MEIJER, BC ^{[1
]}

KOOTSTRA, GJ ^{[1
]}

GEERTSMA, DG ^{[1
]}

WILKINSON, MHF ^{[1
]}

机构：

[1] STATE UNIV GRONINGEN,MED MICROBIOL LAB,9713 EZ GRONINGEN,NETHERLANDS

来源：

EPIDEMIOLOGY AND INFECTION | 1991年 / 106卷 / 03期

关键词：

D O I：

10.1017/S0950268800067571

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In order to elucidate the effect of ceftriaxone therapy on the morphology of gut microflora, 11 human volunteers were treated with ceftriaxone, 1 g daily, given intramuscularly in one dose. Treatment continued for 5 days. Faecal microflora was analysed by digital image processing before, during and after the treatment period. We derived simple numerical parameters which describe the morphologic composition of the flora. They were significantly influenced by the antibiotic, and returned to their baseline values more than 7 days after treatment was stopped. The procedure holds promise for clinical application.

引用

页码：513 / 521

页数：9

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