CHEMISTRY OF INSECT ANTIFEEDANTS FROM AZADIRACHTA-INDICA .19. A POTENTIAL RELAY ROUTE FOR THE SYNTHESIS OF AZADIRACHTIN

被引：39

作者：

DENHOLM, AA

JENNENS, L

LEY, SV

WOOD, A

机构：

[1] UNIV CAMBRIDGE,DEPT CHEM,CAMBRIDGE CB2 1EW,ENGLAND

[2] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

TETRAHEDRON | 1995年 / 51卷 / 23期

关键词：

D O I：

10.1016/0040-4020(95)00297-L

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A potential relay route for the synthesis of azadirachtin (1) has been established. An advanced intermediate 4 has been prepared and methods to convert this back to the natural product have been developed, in particular, the reintroduction of the enol double bond using an acetal exchange process.

引用

页码：6591 / 6604

页数：14

共 24 条

[1] CHEMISTRY OF INSECT ANTIFEEDANTS FROM AZADIRACHTA-INDICA .7. PREPARATION OF AN OPTICALLY PURE HYDROXYACETAL EPOXIDE RELATED TO AZADIRACHTIN [J].