THE EXPRESSION OF 5T4 ANTIGEN IN COLORECTAL AND GASTRIC-CARCINOMA

被引：70

作者：

STARZYNSKA, T ^{[1
]}

RAHI, V ^{[1
]}

STERN, PL ^{[1
]}

机构：

[1] CHRISTIE HOSP NHS TRUST,PATERSON INST CANC RES,CANC RES CAMPAIGN,DEPT IMMUNOL,MANCHESTER M20 9BX,ENGLAND

来源：

BRITISH JOURNAL OF CANCER | 1992年 / 66卷 / 05期

关键词：

D O I：

10.1038/bjc.1992.375

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The expression of 5T4, an oncotrophoblast cell surface antigen was examined in 72 colorectal and 27 gastric carcinomas, with immunoperoxidase technique, on frozen sections. Highly significant association was found between 5T4 expression in the malignant cells and metastatic spread. The results suggest that the appearance of 5T4 molecules in cancer cells reflects a change which may contribute to the development of metastatic potential.

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页码：867 / 869

页数：3

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