NEUROPSYCHOLOGICAL CORRELATES OF ALOGIA AND AFFECTIVE FLATTENING IN SCHIZOPHRENIA

被引：66

作者：

STOLAR, N ^{[1
]}

BERENBAUM, H ^{[1
]}

BANICH, MT ^{[1
]}

BARCH, D ^{[1
]}

机构：

[1] UNIV ILLINOIS, DEPT PSYCHOL, CHAMPAIGN, IL 61820 USA

来源：

BIOLOGICAL PSYCHIATRY | 1994年 / 35卷 / 03期

关键词：

ALOGIA; AFFECTIVE FLATTENING; SCHIZOPHRENIA; TEMPOROLIMBIC SYSTEM; NEUROPSYCHOLOGICAL APPROACH;

D O I：

10.1016/0006-3223(94)91148-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We examined whether two negative symptoms, alogia and affective flattening, were more strongly associated with dysfunction of certain brain regions than with others in a sample of 27 schizophrenic subjects. Neuropsychological tests were used to measure the integrity of functioning of different brain regions. Functioning of left and right frontal regions was assessed by word fluency and design fluency, respectively, and functioning of the left temporohippocampal region was assessed by Hebb's digit-sequences recall rest. Measures of alogia and affective flattening were obtained using the Scale for the Assessment of Negative Symptoms. The results indicated that more severe levels of these negative symptoms were associated with poorer performance on the fluency tests. These relationships were fairly specific as indicated in two ways: (I) only certain neuropsychological measures were associated with negative symptoms; and (2) poor performance on fluency rests was not associated with all psychiatric symptoms. In addition, affective flattening, but not alogia, appeared to be associated with lateralized dysfunction.

引用

页码：164 / 172

页数：9

共 41 条

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[2]

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