COAGULASE EXPRESSION IN STAPHYLOCOCCUS-AUREUS IS POSITIVELY AND NEGATIVELY MODULATED BY AN AGR-DEPENDENT MECHANISM

被引：34

作者：

LEBEAU, C

VANDENESCH, F

GREENLAND, T

NOVICK, RP

ETIENNE, J

机构：

[1] FAC MED ALEXIS CARREL,DEPT RECH BACTERIOL MED EA 1655,F-69372 LYON 03,FRANCE

[2] HOP LOUIS PRADEL,IMMUNOL & PATHOL PULM LAB,F-69394 LYON 03,FRANCE

[3] NYU,MED CTR,SKIRBALL INST BIOMOLEC MED,NEW YORK,NY 10016

来源：

JOURNAL OF BACTERIOLOGY | 1994年 / 176卷 / 17期

关键词：

D O I：

10.1128/JB.176.17.5534-5536.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Expression of staphylocoagulase by agr(+) Staphylococcus aureus depends on the growth phase, being maximal during exponential growth and decreasing sharply postexponentially, while an agr-deleted strain continuously expresses an intermediate level of coagulase. Therefore, coagulase expression appears to be both positively and negatively modulated by an agr-dependent mechanism.

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页码：5534 / 5536

页数：3

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