EXPRESSION OF LYMPHOID-ASSOCIATED ANTIGENS IN MAST-CELLS - REPORT OF A CASE OF SYSTEMIC MAST-CELL DISEASE

被引：29

作者：

ESCRIBANO, L

ORFAO, A

VILLARRUBIA, J

CERVERO, C

VELASCO, JL

MARTIN, F

SANMIGUEL, JF

NAVARRO, JL

机构：

[1] HOSP RAMON Y CAJAL,SERV HEMATOL,E-28034 MADRID,SPAIN

[2] UNIV SALAMANCA,SERV CENT CITOMETRIA,E-37008 SALAMANCA,SPAIN

[3] UNIV SALAMANCA,HOSP CLIN,SERV HEMATOL,E-37008 SALAMANCA,SPAIN

[4] HOSP PROV,MED INTERNA SERV,ZAMORA,SPAIN

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1995年 / 91卷 / 04期

关键词：

SYSTEMIC MAST CELL DISEASE; IMMUNOPHENOTYPE; LYMPHOID-ASSOCIATED ANTIGENS; MAST CELLS; FLOW CYTOMETRY;

D O I：

10.1111/j.1365-2141.1995.tb05417.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this study the expression of 'classically' considered lymphoid-associated antigens (CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD19, CD20, and CD22) was explored both in peripheral blood (PB) and bone marrow (BM) mast cells (MC) in a case of systemic mast cell disease (SMCD) by means of using multiple stainings and a direct immunofluorescence technique, CD2 and CD22 were expressed in both PB and BM MC, all the remaining lymphoid-associated markers were negative. Our results suggest that the reactivity for both CD2 and CD22 in PB and BM MC would be aberrant.

引用

页码：941 / 943

页数：3

共 10 条

[1] MAST-CELL LEUKEMIA - EVIDENCE FOR BONE-MARROW ORIGIN OF THE PATHOLOGICAL CLONE [J].