VIDEO-ASSISTED THORACOSCOPIC THYMECTOMY FOR MYASTHENIA-GRAVIS

被引:117
作者
YIM, APC [1 ]
KAY, RLC [1 ]
HO, JKS [1 ]
机构
[1] CHINESE UNIV HONG KONG, PRINCE WALES HOSP, DEPT MED, SHA TIN, HONG KONG
关键词
MYASTHENIA GRAVIS; TRANSSTERNAL THYMECTOMY; VIDEO-ASSISTED THORACOSCOPIC SURGERY;
D O I
10.1378/chest.108.5.1440
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Video-assisted thoracoscopic surgery (VATS) provides a new approach to thymectomy. From June 1993 to December 1994, we performed a total of eight thymectomies for myasthenia gravis (MG). There were four male and four female patients with ages ranging from 9 to 76 years. Three of the eight patients had associated thymoma, We believe that complete thymectomy was accomplished in all cases by examination of the thymic bed and resected specimen. There was no mortality or intraoperative complications. The median postoperative hospital stay was 5 days (range, 2 to 37 days). One patient required ventilatory support postoperatively. Clinical improvement was observed in all patients after a mean follow-up of 10 months (range, 2 to 21 months). Compared with a comparable historical group of patients with MG who underwent transsternal thymectomy, the VATS group was associated with significantly less analgesic requirement and shortened hospital stay. We conclude that VAT thymectomy is technically feasible and is associated with a favorable postoperative course compared with the transsternal approach. We believe that complete thymectormy can be achieved by this approach. Further investigation with long-term follow-up is needed to further clarify the role of VAT thynectomy in thoracic surgery.
引用
收藏
页码:1440 / 1443
页数:4
相关论文
共 12 条
[1]  
CHUNG SS, 1994, SURG ENDOSC-ULTRAS, V8, P521
[2]   AN IMPROVED TECHNIQUE TO FACILITATE TRANS-CERVICAL THYMECTOMY FOR MYASTHENIA-GRAVIS [J].
COOPER, JD ;
ALJILAIHAWA, AN ;
PEARSON, FG ;
HUMPHREY, JG ;
HUMPHREY, HE .
ANNALS OF THORACIC SURGERY, 1988, 45 (03) :242-247
[3]   PREDICTING THE NEED FOR POSTOPERATIVE MECHANICAL VENTILATION IN MYASTHENIA-GRAVIS [J].
EISENKRAFT, JB ;
PAPATESTAS, AE ;
KAHN, CH ;
MORA, CT ;
FAGERSTROM, R ;
GENKINS, G .
ANESTHESIOLOGY, 1986, 65 (01) :79-82
[4]  
JARETZKI A, 1988, J THORAC CARDIOV SUR, V95, P747
[5]   RESPONSE TO THYMECTOMY IN CHINESE PATIENTS WITH MYASTHENIA-GRAVIS [J].
KAY, R ;
LAM, S ;
WONG, KS ;
WANG, A ;
HO, J .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1994, 126 (01) :84-87
[6]   THORACOSCOPIC RESECTION OF AN ANTERIOR MEDIASTINAL TUMOR [J].
LANDRENEAU, RJ ;
DOWLING, RD ;
CASTILLO, WM ;
FERSON, PF ;
PAIROLERO, PC .
ANNALS OF THORACIC SURGERY, 1992, 54 (01) :142-144
[7]   PREDICTION OF THE NEED FOR POSTOPERATIVE MECHANICAL VENTILATION IN MYASTHENIA-GRAVIS [J].
LEVENTHAL, SR ;
ORKIN, FK ;
HIRSH, RA .
ANESTHESIOLOGY, 1980, 53 (01) :26-30
[8]  
OLANOW CW, 1987, ANN NY ACAD SCI, V505, P595
[9]  
OSSERMAN KE, 1971, MT SINAI J MED, V38, P497
[10]   ROLE OF STAGING IN PROGNOSIS AND MANAGEMENT OF THYMOMA [J].
WILKINS, EW ;
GRILLO, HC ;
SCANNELL, JG ;
MONCURE, AC ;
MATHISEN, DJ .
ANNALS OF THORACIC SURGERY, 1991, 51 (06) :888-892