A DINUCLEAR (MU-CARBOXYLATO)MANGANESE(II) COMPLEX DERIVED FROM A MACROCYCLIC LIGAND - A STRUCTURAL MODEL FOR ACTIVE-SITES IN NATURAL SYSTEMS

被引：27

作者：

ADAMS, H

BAILEY, NA

DEBAECKER, N

FENTON, DE

KANDA, W

LATOUR, JM

OKAWA, H

SAKIYAMA, H

机构：

[1] UNIV SHEFFIELD, DEPT CHEM, SHEFFIELD S3 7HF, S YORKSHIRE, ENGLAND

[2] CEN, DRFMC SESM LABS, F-38041 GRENOBLE, FRANCE

[3] WAKAYAMA UNIV, FAC EDUC, WAKAYAMA, JAPAN

[4] KYUSHU UNIV, FAC SCI, DEPT CHEM, FUKUOKA 812, JAPAN

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1995年 / 34卷 / 22期

关键词：

COMPLEXES WITH NITROGEN LIGANDS; ENZYMES; MANGANESE COMPOUNDS; D-XYLOSE ISOMERASE;

D O I：

10.1002/anie.199525351

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Even in solution only a single μ‐carboxylato bridge links the metal centers in complex 1, according to EPR studies. This feature makes the complex an interesting structural model for the active center in enzymes that contain two manganese atoms. In D‐xylose isomerase, for example, the manganese atoms are linked by a single bridging carboxylate(glutamate) residue. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：2535 / 2537

页数：3

共 22 条

[1] ADAMS H, 1993, SUPRAMOL CHEM, V2, P325
[2] STRUCTURALLY DIVERSE MANGANESE(III) CARBOXYLATE COMPLEXES OF N2O2 DONOR SET SYMMETRICAL SCHIFF-BASE LIGANDS
AURANGZEB, N
HULME, CE
MCAULIFFE, CA
PRITCHARD, RG
WATKINSON, M
BERMEJO, MR
SOUSA, A
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (18) : 2193 - 2195
[3] BARYNIN VV, 1986, DOKL AKAD NAUK SSSR+, V288, P877
[4] PSEUDOCATALASE FROM LACTOBACILLUS-PLANTARUM - EVIDENCE FOR A HOMOPENTAMERIC STRUCTURE CONTAINING 2 ATOMS OF MANGANESE PER SUBUNIT
BEYER, WF
FRIDOVICH, I
[J]. BIOCHEMISTRY, 1985, 24 (23) : 6460 - 6467
[5] X-RAY-ANALYSIS OF D-XYLOSE ISOMERASE AT 1.9 A - NATIVE ENZYME IN COMPLEX WITH SUBSTRATE AND WITH A MECHANISM-DESIGNED INACTIVATOR
CARRELL, HL
GLUSKER, JP
BURGER, V
MANFRE, F
TRITSCH, D
BIELLMANN, JF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (12) : 4440 - 4444
[6] CHE CM, 1991, J CHEM RES-S, P30
[7] MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING-OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT
COLLYER, CA
HENRICK, K
BLOW, DM
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 212 (01) : 211 - 235
[8] Dismukes, 1993, BIOINORGANIC CATALYS
[9] XYLOSE ISOMERASE
HOCHSTER, RM
WATSON, RW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (13) : 3284 - 3285
[10] PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES-MISSOURIENSIS .1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL-BINDING SITES
JENKINS, J
JANIN, J
REY, F
CHIADMI, M
VANTILBEURGH, H
LASTERS, I
DEMAEYER, M
VANBELLE, D
WODAK, SJ
LAUWEREYS, M
STANSSENS, P
MRABET, NT
SNAUWAERT, J
MATTHYSSENS, G
LAMBEIR, AM
[J]. BIOCHEMISTRY, 1992, 31 (24) : 5449 - 5458

← 1 2 3 →