THE 1ST INTERNATIONAL UROKINASE WARFARIN TRIAL IN COLORECTAL-CANCER

被引：33

作者：

DALY, L

机构：

[1] Department of Community Medicine and Epidemiology, University College, Dublin, Earlsfort Terrace

来源：

CLINICAL & EXPERIMENTAL METASTASIS | 1991年 / 9卷 / 01期

关键词：

D O I：

10.1007/BF01831705

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Three hundred and forty-four patients with operable colorectal adenocarcinoma, Dukes' stage B or C, were entered into a randomized controlled trial of intraoperative and postoperative intravenous urokinase and/or long-term sodium warfarin therapy. The factorial design of the trial allowed evaluation of each therapy separately. Age, sex, Dukes' stage and cancer site were similar in the treatment groups. Using life-table methods, survival and recurrence/metastases free survival were estimated up to 6 years postoperatively. No significant effects of either therapy on these endpoints were found.

引用

页码：3 / 11

页数：9

共 18 条

[1]

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[2]

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