RISK-FACTORS FOR POSTVITRECTOMY FIBRIN FORMATION

被引:22
作者
JAFFE, GJ [1 ]
SCHWARTZ, D [1 ]
HAN, DP [1 ]
GOTTLIEB, M [1 ]
HARTZ, A [1 ]
MCCARTY, D [1 ]
MIELER, WF [1 ]
ABRAMS, GW [1 ]
机构
[1] MED COLL WISCONSIN,MILWAUKEE,WI 53226
关键词
D O I
10.1016/S0002-9394(14)72434-1
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
We prospectively studied 194 patients undergoing vitrectomy between July 1988 and April 1989 to determine the incidence of postvitrectomy intraocular fibrin formation and the association of a variety of preoperative and intraoperative variables with the formation of severe postvitrectomy fibrin. Overall, 62 (32%) patients developed postvitrectomy fibrin; 25 (13%) had mild fibrin formation, 13 (6.5%) had moderate fibrin formation, and 24 (12.4%) had severe fibrin formation. By logistic multivariate analysis, preoperative factors that were independently predictive of severe fibrin formation included severe flare (P = .004), the presence of a previously placed scleral buckle (P = .001), and poor preoperative visual acuity (P = .007). Anterior epiretinal membrane dissection was the only intraoperative factor that was independently associated with an increased fibrin risk (P = .0003). A risk score derived from the multivariate analysis effectively categorized patients according to their likelihood of developing severe postvitrectomy fibrin. Results of this study may be useful in designing prophylactic interventions to decrease postvitrectomy fibrin formation.
引用
收藏
页码:661 / 667
页数:7
相关论文
共 18 条
[1]  
AABERG T M, 1985, P503
[2]  
DABBS CK, 1989, INVEST OPHTHALMOL S, P273
[3]   PUPILLARY STRETCHING - A NEW PROCEDURE IN VITREOUS SURGERY [J].
ECKARDT, C .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 1985, 5 (04) :235-238
[4]  
HAN DP, 1989, INVEST OPHTHALMOL S, P272
[5]  
IVERSON D, 1989, INVEST OPHTHALMOL S, P273
[6]   TREATMENT OF POSTVITRECTOMY FIBRIN PUPILLARY BLOCK WITH TISSUE PLASMINOGEN-ACTIVATOR [J].
JAFFE, GJ ;
LEWIS, H ;
HAN, DP ;
WILLIAMS, GA ;
ABRAMS, GW .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1989, 108 (02) :170-175
[7]  
JAFFE GJ, IN PRESS OPHTHALMOLO
[8]   WHEN DOES THE FAILURE TO FIND A DIFFERENCE MEAN THAT THERE IS NONE [J].
JAVITT, JC .
ARCHIVES OF OPHTHALMOLOGY, 1989, 107 (07) :1034-1040
[9]  
JOHNSON RN, 1988, OPHTHALMOLOGY, V95, P312
[10]  
KIMURA SJ, 1959, AM J OPHTHALMOL, V47, P155