BASE PAIR OPENING PATHWAYS IN B-DNA

被引：36

作者：

RAMSTEIN, J ^{[1
]}

LAVERY, R ^{[1
]}

机构：

[1] INST BIOL PHYS CHIM,F-75005 PARIS,FRANCE

来源：

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 1990年 / 7卷 / 04期

关键词：

D O I：

10.1080/07391102.1990.10508532

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular modeling is used to study the opening pathways of bases within a B-DNA oligomer. It is demonstrated that many open states are possible for a single base pair, although a preference for opening towards the major groove of the double helix is found. In addition we show that opening is strongly influenced by the nature of the base involved and is also coupled in many cases to DNA bending. © 1990 Adenine Press.

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页码：915 / 933

页数：19

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