SYNTHESIS OF 15-KETO-6-BETA,7-BETA-METHYLENEPROGESTERONE - EFFECT OF 6-BETA,7-BETA-METHYLENE GROUP ON MINERALOCORTICOID ACTIVITY

被引：6

作者：

CHINN, LJ ^{[1
]}

DESAI, BN ^{[1
]}

机构：

[1] GD SEARLE & CO,LABS DIV,DEPT CHEM RES,CHICAGO,IL 60680

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1975年 / 18卷 / 03期

关键词：

D O I：

10.1021/jm00237a011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：268 / 271

页数：4

相关论文

共 18 条

[1] ARTH GE, 1974, TETRAHEDRON LETT, P291
[2] BARBER GW, 1957, LIEBIGS ANN CHEM, V603, P89
[3] 3-(16BETA,17BETA-DIHYDROXY-3-OXOANDROST-4-EN-17 ALPHA-YL)PROPIONIC ACID GAMMA-LACTONE, ITS PREPARATION AND ANTIMINERALOCORTICOID ACTIVITY
CHINN, LJ
HOFMANN, LM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (07) : 839 - 843
[4] DIMETHYLSULFOXONIUM METHYLIDE
COREY, EJ
CHAYKOVSKY, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (05) : 867 - &
[5] STEROIDS .7. CONTRIBUTION TO THE BROMINATION OF DELTA-4-3-KETOSTEROIDS AND A NEW PARTIAL SYNTHESIS OF THE NATURAL ESTROGENS
DJERASSI, C
ROSENKRANZ, G
ROMO, J
KAUFMANN, S
PATAKI, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1950, 72 (10) : 4534 - 4540
[6] DJERASSI C, 1958, LIEBIGS ANN CHEM, V612, P93
[7] DYSON NH, 1966, TETRAHEDRON LETT, P1841
[8] Hansch C., 1971, DRUG DESIGN, V11, P271
[9] JOHNS WF, 1973, 166 NAT M AM CHEM SO
[10] ISOLATION AND IDENTIFICATION OF NOVEL SULFUR-CONTAINING METABOLITES OF SPIRONOLACTONE (ALDACTONE-R)
KARIM, A
BROWN, EA
[J]. STEROIDS, 1972, 20 (01) : 41 - &