CYTOCHALASIN-U AND CYTOCHALASIN-V, 2 NEW CYTOCHALASINS, FROM PHOMA-EXIGUA VAR HETEROMORPHA

被引：14

作者：

EVIDENTE, A

LANZETTA, R

CAPASSO, R

VURRO, M

BOTTALICO, A

机构：

[1] UNIV NAPLES,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

[2] CNR,IST TOSSINE & MICOTOSSINE PARASSITI VEGETALI,I-70125 BARI,ITALY

来源：

TETRAHEDRON | 1992年 / 48卷 / 30期

关键词：

D O I：

10.1016/S0040-4020(01)88222-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two additional cytochalasins were isolated from liquid culture filtrates of Phoma exiqua var. heteromorpha together with some already known cytochalasins. The two new metabolites, named cytochalasin U and V, represent the first natural occurrence of a 25,26-dioxa[16] and 25-oxa[15]cytochalasan, respectively, both bearing a formyl group on the macrocyclic ring. Cytochalasins U and V showed respectively significant and weak activity in the brine shrimp assay.

引用

页码：6317 / 6324

页数：8

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