EFFECT OF VARIOUS PARAMETERS ON SODIUM DODECYL-SULFATE (SDS) FLUX THROUGH A COLLAGEN MEMBRANE

被引：3

作者：

GARCIA, MT ^{[1
]}

LEAL, JS ^{[1
]}

RIBOSA, I ^{[1
]}

机构：

[1] ASOCIAC INVEST DETERGENTES, E-08034 BARCELONA, SPAIN

来源：

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY | 1992年 / 69卷 / 01期

关键词：

COLLAGEN; DIFFUSION; PERMEABILITY; SDS; SURFACTANT;

D O I：

10.1007/BF02635870

中图分类号：

O69 [应用化学];

学科分类号：

081704 [应用化学];

摘要：

The influence of various experimental parameters on the flux of sodium dodecyl sulfate (SDS) through a collagen membrane has been studied. The variables evaluated were donor concentration, time, temperature, pH and ionic strength. Data on the influence of both surfactant concentration and time on surfactant diffusion through the collagen film allow one to postulate a diffusion process mainly of the monomeric type. This diffusion mechanism based on surfactant monomers has been corroborated by studying the effect of ionic strength. This in vitro technique could be a useful tool to predict the effect of diverse experimental parameters on the percutaneous absorption of surfactants.

引用

页码：20 / 24

页数：5

共 8 条

[1]

PERMEATION OF ESTRONE, ESTRADIOL, ESTRIOL AND DEXAMETHASONE ACROSS CELLULOSE-ACETATE MEMBRANE [J].