HIGH-RESOLUTION H-1-NMR IN SOLID-PHASE ORGANIC-SYNTHESIS

被引：200

作者：

FITCH, WL

DETRE, G

HOLMES, CP

SHOOLERY, JN

KEIFER, PA

机构：

[1] NMR CONSULTANT,PALO ALTO,CA 94306

[2] VARIAN NMR INSTRUMENTS,PALO ALTO,CA 94304

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 26期

关键词：

D O I：

10.1021/jo00105a006

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for obtaining H-1 NMR spectra of organic molecules covalently attached to solid-phase synthesis beads using magic angle spinning in a conventional spectrometer is described. The new method offers substantial qualitative and quantitative advantages and makes 1H NMR truly available as an analytical tool to the solid-phase synthesis practitioner.

引用

收藏

页码：7955 / 7956

页数：2

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