DIRECT ROLE OF LINOLEIC-ACID IN BARRIER FUNCTION - EFFECT OF LINOLEIC-ACID ON THE CRYSTALLINE-STRUCTURE OF OLEIC-ACID OLEATE MODEL STRATUM-CORNEUM LIPID

被引：6

作者：

FRIBERG, SE ^{[1
]}

KAYALI, I ^{[1
]}

RHEIN, L ^{[1
]}

机构：

[1] COLGATE PALMOLIVE CO,PISCATAWAY,NJ 08854

来源：

JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY | 1990年 / 11卷 / 01期

关键词：

D O I：

10.1080/01932699008943234

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An explanation for the direct role of linoleic acid in barrier function is offered based on the fact that the formation of a crystalline state of the hydrocarbon chains in the stratum corneum lipids strongly reduces or entirely removes the barrier. Addition of linoleic acid to a gel liquid crystalline structure of oleic acid/sodium oleate, a model for stratum corneum lipids, prevents crystallization of the hydrocarbon chains when the water content is reduced. Thus the presence of unsaturation in the fatty acid/soap is not sufficient to prevent cyrstallization rather inclusion of the essential fatty acid, linoleic acid, will retain the liquid crystalline structure necessary for normal barrier function over a wide range of relative humidities. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：31 / 47

页数：17

共 14 条

[1] CRYSTAL STRUCTURE OF LOW-MELTING FORM OF OLEIC ACID [J].