ADHERENCE OF MALASSEZIA-FURFUR TO HUMAN STRATUM-CORNEUM CELLS IN-VITRO - A STUDY OF HEALTHY-INDIVIDUALS AND PATIENTS WITH SEBORRHEIC DERMATITIS

被引:6
作者
BERGBRANT, IM
FAERGEMANN, J
机构
[1] Department of Dermatology and Venereology, Sahlgrenska University Hospital, Götteborg
关键词
MALASSEZIA FURFUR; ADHERENCE; STRATUM CORNEUM CELLS; SEBORRHEIC DERMATITIS; AGE VARIATION;
D O I
10.1111/j.1439-0507.1994.tb00303.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The role of Malassezia furfur adherence to human stratum corneum cells in vitro was studied. The adherence assay was performed with one strain of M. furfur and stratum corneum cells from 30 healthy individuals and from 28 patients with seborrhoeic dermatitis. Stratum corneum cells from patients with seborrhoeic dermatitis contained significantly lower numbers of adherent M. furfur cells than cells from healthy individuals. No correlation was found with sex or age. The adherence assay was also performed with stratum corneum cells from one healthy individual and M. furfur strains from 15 patients with seborrhoeic dermatitis and 13 healthy controls. Malassezia furfur strains from patients with seborrhoeic dermatitis showed the same in vitro capacity for adherence to stratum corneum cells as strains from healthy individuals. This in vitro study does not indicate that M. furfur adherence to human stratum corneum cells is of importance in the pathogenesis of seborrhoeic dermatitis.
引用
收藏
页码:217 / 219
页数:3
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